Mediterranean diet protects against cardiovascular diseases via the intestinal flora – healing practice

How the Mediterranean diet protects the heart

Die mediterranean diet comes with a variety of benefits, including an improved one cardiovascular health. The Mediterranean diet seems to be the Darmflora in such a way that their metabolites improve cardiovascular health.

In a new study involving experts from Barcelona University (UB) examined the association between microbial phenolic metabolites, adherence to the Mediterranean diet, and cardiovascular health. The results are published in the English-language journal “Food Research International” released.

Effect of the Mediterranean diet investigated

The team performed a cross-sectional analysis of the data from the PREDIMED-Study (PREvención con DIeta MEDiterránea) by showing the effect of traditional Mediterranean nutrition on the primary prevention of cardiovascular diseases was investigated.

This investigation included a total of 7,447 participants between the ages of 55 and 80. Participated in the current investigation 200 randomly selected participants of the PREDIMED study.

The researchers succeeded five different relevant microbial phenolic metabolites to identify. Such metabolites are produced by microorganisms such as bacteria and mushrooms as degradation products Polyphenolen produced in plant foods.

The microbial phenolic metabolites can provide health benefits such as a anti-inflammatory and antioxidant Effect.

The five identified microbial phenolic metabolites included: protocatechuic acid (PCA), enterodiol glucuronide (EDG), enterolactone glucuronide (ELG), vanillic acid glucuronide (VAG) and urolithin B glucuronide (UBG), the experts report.

Among the polyphenols from the Mediterranean diet, phenolic compounds have a poor bioavailability and yet they are ingested by the gut microbiota highly metabolizedexplains the team.

Higher levels of phenolic metabolites

Overall, better compliance with the mediterranean diet with higher levels of microbial phenolic metabolites in urine and better cardiovascular health been associated. Individual microbial phenolic metabolites were particularly clearly associated with positive effects on cardiovascular health.

Further analyzes showed that there was an inverse connection between one of the polyphenols examined and one that was often described as unhealthy LDL cholesterol consists. It was regarding Urolithin B-Glucuronid.

LDL cholesterol can build up on the walls blood vessels deposit, leading to the formation of so-called Plaques leads. These plaques can constrict blood vessels and increase the risk of heart diseases, heart attacks and strokes increase.

At high values ​​of Urolithin B-Glucuronid LDL cholesterol levels tended to be lower in the current study.

Positive effect mediated via the intestinal flora

Die mediterranean diet may affect the Darmflora have and their metabolites are enhanced with cardiovascular health connected, the researchers summarize. (as)

Author and source information

This text corresponds to the requirements of medical specialist literature, medical guidelines and current studies and has been checked by medical professionals.

Sources:

  • Ines Dominguez-Lopez, Camile Arancibia-Riveros, Montserrat Fito, Ramon Estruch, Estefania Toledo, et al.: Association of microbiota polyphenols with cardiovascular health in the context of a Mediterranean diet; in: Food Research International (veröffentlicht 24.01.2023), Food Research International

Important NOTE:
This article contains general advice only and should not be used for self-diagnosis or treatment. He can not substitute a visit at the doctor.

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