2023-07-18 22:00:00
As early as Antiquity, our ancestors already thought that fermented foods were beneficial for intestinal health, in particular. Since 2021, we have unequivocally admitted the considerable importance of commensal bacteria colonizing the human body for our well-being but also to help resolve multiple pathological events. Until now probiotics, which are live microorganisms, were administered in adequate amounts with the aim of conferring a health benefit. But European regulation n° 2017/745 has just excluded probiotics from medical devices as a precautionary principle: these live bacteria are likely to induce infections such as sepsis, or to transmit antibiotic resistance genes. To remedy these drawbacks, most often thermal treatments (in particular by pasteurization or by tyndallization) of bacterial suspensions, in particular of probiotics, have been implemented to transform them into “inanimate” bacteria: postbiotics.
This article presents the benefits of postbiotics and their acellular supernatants, which are also capable of conferring beneficial effects in various pathologies.
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