Low-Dose Aspirin and Anemia: Understanding the Risk

2023-06-21 23:23:06

“Low-dose aspirin increases risk of anemia”

(Seoul = Yonhap News) Reporter Han Seong-gan = A study has found that elderly people who take low-dose aspirin to prevent cardiovascular and cerebrovascular disease may develop anemia.

Anemia can cause symptoms such as fatigue, shortness of breath, dizziness, arrhythmia, headache, chest pain, and pale or yellow skin.

Dr. Joe McQuilton, a professor of hematology at Monash University Medical School in Australia, and his research team analyzed data from a 5-year clinical trial (ASPirin in Reducing Events) on 19,114 elderly people aged 70 years or older, and found this fact. This was revealed, HealthDay News reported on the 21st.

They were randomly divided into two groups, one group (experimental group) was given a daily low-dose (100mg) aspirin, and the other group (control group) was given a placebo (placebo).

The experimental group was analyzed to have a 24% higher risk of developing anemia within 5 years than the control group.

The experimental group also had a lower hemoglobin (hemoglobin) level in red blood cells that carries oxygen throughout the body than the control group.

The experimental group also had less iron in blood than the control group. Our body uses iron to make hemoglobin.

Therefore, the research team recommended that elderly people taking low-dose aspirin periodically monitor hemoglobin and blood iron levels while keeping an eye on symptoms of anemia such as fatigue and shortness of breath.

Dr. Marguerite Raney, medical director of the Hemophilia Center of Western Pennsylvania and spokesperson for the American Society of Hematology, commented on this as a natural result of aspirin’s effect on platelets.

Aspirin can prevent myocardial infarction and stroke by interfering with the ability of platelets to clot, but it also inhibits small blood clots that prevent blood leakage from the gastrointestinal tract and other body tissues, resulting in bleeding and anemia. can, he explained.

The gastrointestinal tract is a common site for bleeding, and blood loss can occur if this is not prevented, he notes.

Bleeding reduces hemoglobin and blood iron levels, which can lead to anemia.

Even if you don’t, the elderly will develop anemia during the aging process, but aspirin seems to promote anemia more, he added.

The American Heart Association (AHA) recommends that anyone with a history of myocardial infarction or stroke, a history of stenting for coronary artery stenosis, or a history of arrhythmia (atrial fibrillation) take low-dose aspirin in consultation with their doctor.

However, the AHA does not recommend the use of low-dose aspirin for the purpose of preventing a first myocardial infarction or first stroke, as the harm may outweigh the benefits.

The United States Special Committee on Disease Prevention and Prevention (USPSTF) also recommends that seniors over 60 not take low-dose aspirin for the purpose of preventing heart disease.

The findings were published in the online edition of the Annals of Internal Medicine, a journal of the American Academy of Internal Medicine.

skhan@yna.co.kr

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