| From left to right, Seoul National University Hospital Cardiovascular Internal Medicine Professor Kim Hyung-gwan, former physician Park Chan-soon, and Soongsil University Professor Kyung-do Han |
[라포르시안] A new perspective has been presented to the clinic that recommended weight loss for diabetic patients. Diabetes patients who gain or lose more than 5% of their body weight are more likely to develop cardiovascular disease, a study has found.
At Seoul National University Hospital, Professor Kim Hyung-gwan’s team (former doctor Park Chan-soon) and Soongsil University’s Professor Han Kyung-do’s team studied the relationship between weight change and cardiovascular disease in 1,522,241 diabetic patients who underwent comprehensive health checkups twice between 2009 and 2012. On the 8th, it announced that the results of cohort analysis were announced.
According to data from the Korean Diabetes Association, the prevalence of diabetes in Korea is 13.8%. About 1 in 7 adults over the age of 30 are diabetic. Compared to the general population, they are more prone to cardiovascular diseases such as myocardial infarction and stroke, and have a higher mortality rate. In particular, obesity can increase blood cholesterol levels, blood sugar levels, and blood pressure, which are major risk factors for cardiovascular disease. Therefore, under the existing medical guidelines, weight loss was recommended for obese diabetic patients.
However, it has not been proven to what extent weight loss is appropriate or whether weight loss actually helps prevent cardiovascular disease. Therefore, it was necessary to study the effect of weight gain and loss on the prognosis of diabetes in patients.
The research team measured the weight change of 1,522,241 diabetic patients using data from the National Health Insurance Corporation, and reduced the weight by more than 10% ▲5% to 10% weight loss ▲Stable weight (less than 5% increase or decrease) ▲5% to 10% % weight gain ▲ 10% or more weight gain was classified as a group. After regarding 7 years, the occurrence of myocardial infarction, stroke, atrial fibrillation, heart failure and death was followed up.
As a result, compared to the stable weight group, the 5% or more weight loss group had a higher annual cardiovascular disease incidence and mortality rate.
Compared to the 5% to 10% weight loss group, the 10% or more weight gain group showed a greater increase in annual cardiovascular disease incidence and mortality. In other words, there was a U-shaped correlation that the risk of cardiovascular disease and death increased as the patient’s weight increased or decreased.
This correlation was consistently shown in underweight, normal weight, overweight, and obese patients regardless of the degree of obesity in diabetic patients. In other words, it was confirmed that the degree of weight change was more significantly involved in the occurrence of cardiovascular disease in diabetic patients than the degree of obesity.
Professor Kim Hyung-kwan said, “This study is significant in that it revealed that both rapid weight gain and loss in diabetic patients increase the risk of cardiovascular disease, unlike existing guidelines.” “Weight loss in obese diabetic patients.” “If a patient loses weight, it is necessary to comprehensively review how the blood sugar level, diet, and exercise method are being controlled and whether other diseases have occurred,” he said.
This study was published online on the 9th of last month in ‘Diabetes Care’, the most prestigious medical journal in the field of endocrine metabolism.
