[의학신문·일간보사=이상만 기자] As the mortality rate increases when septic shock patients also suffer from sarcopenia, a study found that high-risk groups need protein intake to prevent sarcopenia..
Namsoo Koo, Department of Infectious Diseases, Severance Hospital, Professor Jung-ho Kim’s research team treated patients with septic shock 11As a result of follow-up for years, the highest mortality rate with sarcopenia 26.5% that it increases 12day said. The results of this study were published in an international scientific journal. ‘cachexy·muscle loss·muscle journal’(JCSM·Journal of cachexia, sarcopenia and muscle, IF12.063) published in the latest issue.
Septic shock is a disease in which bacteria invading the body secrete toxic substances and cause inflammation throughout the body.. brain, The function of almost all body organs, including the heart, deteriorates rapidly, leading to a death rate. 60%to reach.
Treatments include administering antibiotics along with a booster to suppress bacterial growth by raising blood pressure and putting on a ventilator to help breathing.. Recently, as the number of immunocompromised persons increases with the active use of chemotherapy and organ transplantation, the incidence of septic shock is also increasing..
body muscle mass, Although sarcopenia, which decreases muscular endurance, has been consistently suggested that it lowers immunity and adversely affects mortality from septic shock., To date, there have been no long-term follow-up studies, making it difficult to confirm specific associations..
the research team 2008from year 11Total number of septic shock patients who visited Severance Hospital emergency treatment center for a year905A study was conducted on the mortality rate according to the presence or absence of sarcopenia.. patients with sarcopenia 407Patients without glia and sarcopenia 498short-term by person(28Work)and middle(1year), long time(11year) Mortality was followed.
Results, Mortality increased when patients with septic shock were accompanied by sarcopenia.. For short-term mortality, patients with sarcopenia 13.8%patients without sarcopenia(6.4%)Compared to 7.4% was high. Patients with sarcopenia even in mid-term mortality(41.8%)patients who are not accompanied by(21.7%)see 20.1% appeared high, As a result of long-term follow-up, the mortality rate of patients with sarcopenia was also 62.2%patients who are not(35.7%)compared to 26.5% was different.
Age that can affect mortality other than sarcopenia, Even following excluding other factors such as comorbidities, if there is sarcopenia, the mortality rate is lower. 1.7twice as high.
They then studied the effect of increased muscle mass on lowering mortality.. If the area of the abdominal muscles is increased compared to the height(1㎠/㎡, Abs area/square of height)in short term, middle term, Long-term mortality is 3.1%, 2.2%, 2.6% decreased.
Professor Namsoo Koo “This study is the first long-term study to reveal the relationship between muscle mass and mortality in septic shock patients.”saying “High-risk groups for septic shock with weakened immunity, such as those undergoing chemotherapy or organ transplant recipients‧milk‧Preventing sarcopenia by eating protein, such as fish, is important in lowering the risk of death”said.
