2023-06-29 17:18:34
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Researchers from the Mayo Clinic and Harvard Medical School have found that the use of hormone therapy during menopause can trigger an increased risk of dementia and Alzheimer’s disease. However, they did not recommend that women stop taking hormones.
Alina Shcheglova
news editor
Unsplash
Hormone replacement therapy is used by women during menopause to relieve unpleasant symptoms such as hot flashes and night sweats. The drugs may contain only estrogen or a combination of estrogen and progestin. These same hormones may contain patches, gels, and creams.
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In the study, scientists from 2000 to 2018 analyzed data from 5.5 thousand women with dementia and 55.9 thousand women without it. All women lived in Denmark, and in 2000 they were 50-60 years old. The researchers controlled for other important risk factors for dementia, including income level, quality of education, and the presence of hypertension, diabetes, and thyroid disease. The work was published in the journal BMJ.
It turned out that compared with women who did not take hormones in menopause, those who received combined estrogen and progestin preparations had a 24% higher incidence of various types of dementia (including Alzheimer’s disease).
The risk of developing dementia in women who took hormones for 12 years or more was 74% higher than in those who did without hormones. Also, a particularly high risk was observed in women under 55 years of age.
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The increased risk of dementia was the same with daily use and cyclic – no more than 14 days per month. According to scientists, this is only a correlation, so you can’t even talk regarding a cause-and-effect relationship. They do not exclude that women receiving hormones simply have a predisposition to dementia. Therefore, conclusions are not enough to cancel hormone therapy.
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#Dementia #related #hormone #therapy #menopause
