On the occasion of World Diabetes Day, which falls on November 14 of each year, we present the most important and latest drugs and treatments that have been put forward and will soon be presented to treat the disease, and complete recovery from diabetes using stem cells, there is an injection of insulin taken weekly instead of daily injections to treat type 1 diabetes And other weekly injections have been introduced globally in the treatment of type 2 diabetes, and are expected to be launched soon in Egypt.
New medicines for diabetics
For her part, Dr. Enas Shaltout, Professor of Internal Medicine and Diabetes at Kasr Al-Ainy Medicine, revealed that in the near future, basal insulin will be released, which works for a week and will relieve a large segment of patients following approval. It is intended for type 1 and type 2 diabetes because it is not injected on a daily basis, but rather on a weekly basis.
She said, that the weekly injections are accepted by the patient psychologically, and it reduces the suffering on the patient because the increase in the number of injections is not adhered to by the patient, explaining that research says that he may miss it several times, and there is a relationship between increasing the number of injections and depression always when we reduce the number of injections he accepts The patient is doing better, and he is in the third phase of experiments, where there are two bodies that are conducting the study on him, namely Denmark, which is “famous in producing insulin” and “the United States of America.”
She added, that among the treatments that will represent good news for a diabetic if successful, there are a few cases that have achieved success in the field of stem cells and one patient was cured during the study, and there are other people who are being studied on, and it will represent good news for patients because it may be a curative treatment for type diabetes. The first, but we must wait until these experiments are completed and stem cell therapy is proven following 5 years of trying the treatment on the patient first to make sure of its success, and secondly to make sure that no complications occur, and following a person has recovered from diabetes and there are experiments on and we wait for 5 years to be sure of recovery complete.
She said, that the most important drug currently in the world and awaiting approvals for its entry into Egypt is Tirzepatide, which is similar to two substances that are secreted inside the body, and the drug consists of these two substances “GLP1 and GIP” and their function is that they supply insulin secretion from the pancreas, and secondly, they have Effect on the brain to reduce appetite, and they have an effect on the stomach because it makes the patient feel full, and thus benefit in lowering the blood sugar level and reducing body weight by more than 10% of the basic weight of the body, and in some patients the weight reduction reached 20%.
Healthy eating is necessary
She explained that one of its benefits is that it reduces risk factors for the heart and blood vessels, improves blood fats and reduces cumulative sugar from 1.2 to 2.5%, and therefore it is considered a strong treatment for diabetics, and it was approved by the US Food and Drug Administration “FDA”, and it was put on the market in the world, but the cost of Treatment of this type is very expensive and is intended for the second type of diabetes, and it is a weekly injection that makes the patient live normally, adding, that it works to reduce weight and then reduce the medications that the patient takes.
She explained, as for the medicines that are already in Egypt, during the last three years, injections for the second type of sugar contain basal insulin with similar to GLP1 and both in one injection, and basal insulin reduces fasting sugar and GLP1 analogs work to reduce sugar following meals and give These two drugs in one injection work to reduce the cumulative sugar significantly, up to 4% of the glycated hemoglobin, and they are daily injections for the type 2 diabetic, and two types of them were launched in the Egyptian market.
She said, as for the second drug that was launched in Egypt, it is the drug “Simaglutide”, which is the scientific name of the drug, which is tablets instead of injections, and it reduces weight and does not cause a drop in the level of natural sugar, and works to increase the secretion of insulin from the pancreas, and reduces the production of Glucose is supplied by the liver, and it works on the appetite centers in the brain and reduces appetite. It was in the form of injections, and now it is in the form of tablets, and injections are used in the field of weight reduction and treatment of diabetes as well.
Dr. Enas Shaltout added that the use of modern technology in the field of insulin injection method for patients with type 1 diabetes, adding that this type is very expensive, which is the artificial pancreas, which is a new technology for insulin injection according to blood sugar levelIt is the same idea as the insulin pump, but it is better developed, as it increases insulin secretion when sugar is high, and reduces insulin secretion when sugar is low. It is a sophisticated technology similar to the insulin pump technology, but it is more sophisticated, and it is very expensive.
