2023-08-25 13:26:54
Colorectal cancer rates among young people might double by 2030
Enter 2023.08.24 15:00 Hits 1,257 Enter 2023.08.24 15:00 Edit 2023.08.24 11:42 Hits 1,257
A high-fat diet represented by ‘junk food’ can also lead to the prevalence of colorectal cancer among young people, a study has announced. [사진= 게티이미지뱅크]As the incidence of colorectal cancer is increasing worldwide, colorectal cancer is becoming prevalent among young people. According to a study published in JAMA, the journal of the American Medical Association, the incidence of colorectal cancer among young people is expected to double by 2030, and colorectal cancer is expected to become the leading cause of cancer deaths among those under 50 in the next 10 years. . The American Cancer Society (ACS) estimates that 19,500 of the 153,000 colorectal cancer patients this year will be under the age of 50.
What is the reason for the prevalence of colorectal cancer in young people? There may be several causes, but a high-fat diet represented by ‘junk food’ can also lead to the prevalence of colon cancer among young people, a study has announced.
According to the British daily newspaper ‘Daily Mail’, researchers from the Salk Institute, a world-renowned life science research institute in the United States, and the University of California, San Diego, found that a high-fat diet increases the risk of colorectal cancer by altering intestinal bacteria and digestive molecules called bile acids, causing inflammation. found.
By elevating bile acid levels in mice on a fast-food-mimicking high-fat diet, the researchers found that the modified bile acids affected stem cell production in the gut. Stem cells, if not sufficiently replenished, can develop mutations that promote cancer cell growth.
Changes in bile acids block a key protein in the intestine called farnesoid X receptor (FXR), increasing the prevalence of colorectal cancer. Bile acids are molecules produced by the liver that help the intestine digest food and absorb cholesterol, fats, and nutrients.
“A high-fat diet alters the composition of the microbiome, allowing the growth of bacteria that promote bile acid production, leading to a vicious cycle of cancer-causing inflammation,” said the researchers. “We identified specific microbial strains that proliferate on high-fat diets.”
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