The university’s neuroscientist, Robert Wood Johnson, linked the microorganisms in… Digestive (known as the gut microbiome) and MS.
For his part, professor of neuroscience and senior author of the study, Koichi Ito, said in a statement: "It may be unhealthy eating habits such as low fiber and high consumption Fats It has contributed to the sharp rise of MS in the United States, and its decline in other countries that follow Diets different".
What is MS?
Multiple sclerosis is one of immune diseases Endogenous, affects the central nervous system.
Cases associated with sclerosis begin to develop with the beginning of the influence of the surrounding neurons (myelin) that protect the nerves, which leads to blocking the path of signals sent to the brain and spinal cord, and from the brain to the rest of the body, which causes symptoms that include the following, according to the website. "Cleveland Clinic" Medical:
- Vision disturbances or eye pain.
- muscle weakness or tremor;
- Difficulty with balance and motor coordination.
- dizziness or asthenia;
- Problems with thinking and memory.
- A feeling of numbness, tingling, or tingling.
– The researchers do not yet know the confirmed causes behind what affects the cells, but they found that MS is not transmitted genetically, nor is it a type of diseases that are transmitted from one person to another.
Multiple sclerosis is unpredictable, and affects people in different ways, as its effect is moderate for some, while it may affect functional abilities for others.
Depending on the severity of the disease, symptoms can go away for a while and then reappear.
What are the results of the new study?
- Many previous studies have distinguished the gut microbiomes of MS patients and healthy individuals, but according to Professor Ito, all of these previous projects have detected various abnormalities, making it nearly impossible to determine which change, if any, was driving the development of the disease.
- In the study, using mice modified with genes linked to multiple sclerosis, the researchers tracked the link between changes in gut bacteria and an MS-like condition known as Brain inflammation and experimental autoimmune marrow.
- As the rodents got older, the mice developed encephalomyelitis, enterocolitis, and encephalitis.
- The researchers monitored increased recruitment of inflammatory cells in the colon and antigen protein production for microbes known as "Lipocalin 2".
- The researchers built on the findings to see if the same thing might happen in people diagnosed with multiple sclerosis.
- The team recorded a high level of performance "Lipocalin 2" In patients’ stool samples, marker levels increased enteritis; other.
- The researchers also found bacteria known to mitigate inflammatory bowel disease in lower amounts among MS patients who had higher levels of IBD "Lipocalin 2" in feces, according to the study, the results of which were published in the journal "Immunology".
- The study also indicated that a high-fiber diet reduces gut inflammation, and thus may also help fight MS.
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According to researchers at Rutgers University, eating foods rich in fiber slows disease Multiple sclerosisAccording to experiments conducted on genetically modified mice.
The university’s neuroscientist, Robert Wood Johnson, linked the microorganisms in… Digestive (known as the gut microbiome) and MS.
For his part, Professor of Neuroscience and senior author of the study, Koichi Ito, said in a statement: “Unhealthy dietary habits such as low fiber and high consumption of Fats It has contributed to the sharp rise of MS in the United States, and its decline in other countries that follow Diets different.”
What is MS?
Multiple sclerosis is one of immune diseases Endogenous, affects the central nervous system.
Cases associated with sclerosis begin to develop with the beginning of the influence of the surrounding neurons (myelin) that protect the nerves, which leads to blocking the path of signals sent to the brain and spinal cord, and from the brain to the rest of the body, which causes symptoms that include the following, according to the “Cleveland” website. Clinic:
- Vision disturbances or eye pain.
- muscle weakness or tremor;
- Difficulty with balance and motor coordination.
- dizziness or asthenia;
- Problems with thinking and memory.
- A feeling of numbness, tingling, or tingling.
– The researchers do not yet know the confirmed causes behind what affects the cells, but they found that MS is not transmitted genetically, nor is it a type of diseases that are transmitted from one person to another.
Multiple sclerosis is unpredictable, and affects people in different ways, as its effect is moderate for some, while it may affect functional abilities for others.
Depending on the severity of the disease, symptoms can go away for a while and then reappear.
What are the results of the new study?
- Many previous studies have distinguished the gut microbiomes of MS patients and healthy individuals, but according to Professor Ito, all of these previous projects have detected various abnormalities, making it nearly impossible to determine which change, if any, was driving the development of the disease.
- In the study, using mice modified with genes linked to multiple sclerosis, the researchers tracked the link between changes in gut bacteria and an MS-like condition known as Brain inflammation and experimental autoimmune marrow.
- As the rodents got older, the mice developed encephalomyelitis, enterocolitis, and encephalitis.
- The researchers monitored increased recruitment of inflammatory cells in the colon and antigen protein production for microbes Known as “lipocalin 2”.
- The researchers built on the findings to see if the same thing might happen in people diagnosed with multiple sclerosis.
- The team recorded high levels of “lipocalin 2” in patients’ stool samples, and increased levels of the marker enteritis; other.
- The researchers also found bacteria known to mitigate inflammatory bowel disease in lower amounts among MS patients who had higher levels of lipocalin-2 in their stool, according to the study, whose findings were published in the Journal of Immunology.
- The study also indicated that a high-fiber diet reduces gut inflammation, and thus may also help fight MS.
