Researchers from Weill Cornell Medicine (United States) and Oxford University (United Kingdom) showed that even vaccines once morest influenza and measles might help reduce the burden of the disease. covid-19 pandemic.
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Before COVID-19 vaccines were available, public health experts and immunologists suggested immunizing vulnerable populations with other vaccines.
The study, published in the scientific journal Proceedings of the National Academy of Sciences, crystallizes decades of scientific evidence suggesting that the generalized immune-boosting properties of many vaccines may cross-protect patients once morest multiple pathogens.
Before the specific vaccines once morest covid-19, many public health experts and immunologists suggested immunizing vulnerable populations with other vaccines to provide some degree of protection.
“We know that unrelated vaccines have these heterologous effects, and a reasonable person would say that if you use them during a pandemic, it would be beneficial. However, it was unclear how much such an intervention would help, which populations would be better to target or what part of the population would have to receive the unrelated vaccines to have a significant effect, “explains Nathaniel Hupert, one of the leaders of the research.
Using the hello from covid-19 In the winter of 2020-21 that hit the United States following the reopening, the researchers modeled the likely effects of a non-covid-19 vaccine intervention at different times and targeting different populations.
Although they did not specify specific vaccines, the researchers chose cross-protection values consistent with data from previous studies on measles, influenza, tuberculosis, and other immunizations.
They found that an unrelated vaccine that provided only 5 percent protection once morest the covid-19 grave, and that it was administered to only a small part of the population, would have caused a substantial reduction in the number of cases and the use of hospitals.
“Surprisingly, we found a couple of really interesting results from what we put into the mix. While the severity of covid-19 is closely correlated with age, an experimental scenario that modeled the vaccination of everyone over the age of 20. was more effective than strategies targeting only the elderly. This might be because young people tend to have more social contacts between age groups, making them more likely to spread the virus to more vulnerable populations. Timing of vaccination it was also important, as administration during the rising phase of the infection wave had the greatest impact, “Hupert argues.
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