Farnesol: A Breakthrough Compound for Alleviating Age-Related Muscle Deterioration

2023-09-03 18:00:00

Korean researchers found out that ‘Farnesol’, a compound found in plants, helps alleviate muscle deterioration associated with aging. Farnesol is a plant-derived compound that gives the taste and aroma of fruits and aromatic plants. Bae Joo-hyun, a researcher at the School of Medicine at Sungkyunkwan University, conducted a rat experiment to confirm the effect of farnesol, a plant-derived compound that can inhibit muscle loss that occurs with age, and published the study results in the international journal Science Translational Medicine on the 31st (local time). According to the research results, farnesol biochemically transforms a protein called ‘PARIS’ to prevent muscle weakness. The most effective way to minimize muscle loss known so far is to maintain a healthy diet that includes protein, vitamin D, and omega-3 fatty acids, and to exercise regularly. According to previous studies, exercise also promotes the activity of ‘PGC-1α’, a protein that supports metabolism and mitochondrial formation in muscle cells. To prevent age-related muscle degradation, the activity of the PGC-1α protein must not be suppressed. The research team found that the PARIS protein inhibits the activity of PGC-1α and focused on developing a treatment targeting PARIS. Moon Se-young, Dong-A Science Reporter moon09@donga.com #Elixir to stop muscle loss #Farnesol Like Image Sad Image Sad Image Angry Image Share Share Image Recommended Article Recommended Image Article ⓒ Dong-A Ilbo & donga.com
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