2023-05-21 19:43:18
He genome human is he ADN that we have in each of our cells and it was possible to sequence first time in 2003. However, Ricardo Moure He points out that “he had a problem”, since 70% of it belonged to a single person and the remaining 30%, to “a medley of 20 people”.
This was done because, 20 years ago, this process It entailed a very high cost, three billion dollars. Now, it has been possible to sequence the first genomeand set of genomes of 47 different peoplea figure that is expected to reach 350 for 2024. A fact that the expert highlights, since “each one that is added is a brutal advance”, because when studying a disease with a genetic basis “we have much more to look for” and, in addition, “it brings justice and diversity to medicine”.
The first genome sequenced corresponded to a person from europebut it is this pangenome, of those 47 analyzed, 16 are belong to America, six to asiathe one that already existed in Europe and 24 to Africa. The biologist explains that most of the new sequences are from the African continent because it is the one that has more “genetic diversity”. As it is the place where humanity arose, the oldest populations are there, for this reason “the DNA of a person from Mali and another from Mozambique has more differences than that of one from Spain and another from China,” he points out.
Moure stresses the importance of know the genomes of many populations in the worldsince although the genetic information of humans is 99.9% the same, those small differences They mean that medicines do not have the same efficacy in different ethnic groups, do not produce the same side effects or do not have the same predisposition to certain diseases or the same food intolerances. “It serves to improve and bring us precision medicine, bring us a fairer medicine,” he clarifies.
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