2024-05-04 07:44:07
A certain pectin asparagus develops a strong anti-neuroinflammatory effect. By inhibiting inflammation in the nerve tissue, it may also have a therapeutic application Alzheimer’s be assessed.
A research team from Guangdong Pharmaceutical University In a recent study, the pectin polysaccharide AOPB-1-1 was isolated from asparagus and its effect once morest inflammation in the nerve tissue was investigated. The study results are in “International Journal of Biological Macromolecules” published.
Far-reaching positive health effects
Asparagus (Asparagus officinalis) is rich in fibre, amino acids, minerals and vitamins and contains a number of bioactive components such as polysaccharides, steroid saponins and flavonoids, explains the team.
Regular consumption is associated with, among other things, immunomodulatory, antioxidant and antitumor effects, and asparagus is generally considered very healthy, although caution is advised when consuming asparagus if you have any existing diseases.
Asparagus extracts, for example, have a strong anti-arthritic effect and Green asparagus strengthens the intestinal flora. Studies on mice have also shown that aqueous extracts of A. officinalis noticeably improve the animals’ learning and memory functions, reports the Chinese research team.
Newly discovered pectin polysaccharide
To date, however, research has mainly focused on the saponins in asparagus, and only a few studies have investigated the polysaccharides of Asparagus officinalis or their anti-inflammatory activities, the researchers continued.
In the new research work, the experts have now managed to isolate a previously unknown pectin polysaccharide called AOPB-1-1 from asparagus and to fully characterize the structure.
Anti-inflammatory effect
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Specifically, AOPB-1-1 can significantly reduce the levels of inflammatory cytokines, including nitric oxide (NO), tumor necrosis factor α (TNF-α) and interleukin-6 (IL-6) and the expression of inflammatory genes such as cyclooxygenase-2 (COX2) and nitric oxide synthase (iNOS).
Use once morest Alzheimer’s?
The significant anti-neuroinflammatory activity of AOPB-1-1 also suggests its utility as a therapeutic option for the treatment of Alzheimer’s disease, the researchers conclude. (fp)
Author and source information
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This text complies with the requirements of medical literature, medical guidelines and current studies and has been checked by medical professionals.
Sources:
- Junqiang Yang, Yuechan Liao, Chao Cao, Qian Yu, Dawei Zhang, Chunyan Yan: Structural identification and anti-neuroinflammatory effects of a pectin-arabinoglucuronogalactan complex, AOPB-1-1, isolated from Asparagus officinalis; in: International Journal of Biological Macromolecules (veröffentlicht 16.03.2024), sciencedirect.com
- Nutritional composition of green asparagus (Asparagus officinalis L.), edible parts and by-products, and assessment of their effect on the growth of gut-associated bacteria; in: Food Research International (published 09.12.2022), sciencedirect.com
- Satish Kumar, Pratima Srivastava, Sumeet Gupta, Meenakshi Dhanawat, Sapna Rani, Basiru Olaitan Ajiboye, Rupesh K. Gautam: Pharmacological evaluation of different extracts of Asparagus officinalis (Asparagaceae) as analgesic and anti-inflammatory agent; in: Pharmacognosy Research, 2023, phcogres.com
Important note:
This article contains general advice only and should not be used for self-diagnosis or treatment. He cannot replace a visit to the doctor.
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