Today (December 5, 2022), Dr. Chalermchai Boonyaleephan posted a private blockdit “hundred eight thousand nine with Doctor Chalermchai” regarding the new vaccine, stating that he was disappointed !! Both brands of new bi-strain vaccines using mRNA technology weren’t as good as expected.
It is well known that The coronavirus that causes COVID-19 has mutated in sequence. starting with the Wuhan virus strain
And in the next 11 months, many countries were able to develop a vaccine once morest COVID. using the Wuhan virus as a starting point And it works very well, at an effectiveness level of 70 to 95%. Therefore, there are many rapid mutations. Speaking only of the main strains, VOC: Variant of Concern will have alpha, beta, gamma, delta and omikron. Was unable to accelerate research and development to keep up with the aforementioned species
Until the year 2022, the Omicron virus has been the main species that can stand for one year thus giving scientists a long enough time to successfully develop a second-generation 2-strain vaccine by combining the Wuhan strain with the Omicron strain subspecies BA.4/5, which in the United States It was introduced a few months ago and the USCDC collected data between September 14 and November 11, 2022 on 360,000 vaccine recipients. It is an mRNA technology (mRNA), two famous brands and injected to people who have previously injected one type of old vaccine. Whether it’s two needles, three needles or four needles, found an interesting number that The farther it is injected from the original vaccine, the more will only get more immunity and injections in young people will get higher immunity than injections in the elderly
The numbers are that if injected 2-3 months away from the original vaccine, the effectiveness will increase by 28-31% compared to not vaccinating the new version. But if the new booster vaccine is given more than 8 months apart, the effectiveness increases to 43-56%.
43% over 65 years old
48% in people aged 50-64
56% among 18-49 years old
In summary, 1. A new so-called second-generation bi-strain vaccine consists of the Wuhan virus strain and the Omikron virus strain. sub-strain BA. 4/5 2. The efficacy of the second-generation two-strain booster vaccine was slightly better than the first-generation vaccine. When injected 8 months away from the original, it will work better than injecting 2-3 months apart. 4. Immunity will be higher from vaccination in people aged 18-49 than in people aged 50 and over and 5. New vaccines. second It did not give a high efficacy at 70-95% level like when producing the first vaccine, 1st generation to deal with the Wuhan virus.
