“Increase in cardiovascular disease and death rate when body weight fluctuates more than 5% for 2 years”
A U-shaped correlation was found between weight change and cardiovascular disease risk in diabetic patients. Provided by Seoul National University Hospital.
A study in Korea found that diabetic patients with severe weight changes, such as gaining or losing more than 5% in body weight over two years, have a higher risk of cardiovascular disease.
This is the opinion of the research team that the degree of weight change is more involved in the occurrence of cardiovascular disease in diabetic patients than the degree of obesity.
A research team led by Professor Hyung-Kwan Kim of Seoul National University Hospital Department of Cardiology and Professor Kyung-Do Han of Soongsil University confirmed this fact by analyzing the association between weight change and cardiovascular disease of 1,522,421 diabetic patients who underwent comprehensive health checkups twice between 2009 and 2012. said.
The research team classified them into ▲10% or more weight loss ▲5~10% weight loss ▲steady weight (less than 5% increase or decrease) ▲5~10% weight gain ▲10% or more weight gain. The occurrence of atrial fibrillation, heart failure, and death was followed.
As a result, the risk of cardiovascular disease and mortality were higher in the weight gain or loss group of 5% or more compared to the group with stable body weight. The higher the increase/decrease rate, the greater the risk of cardiovascular disease and mortality.
Overall, a ‘U’-shaped correlation was confirmed in that the greater the patient’s weight gain or loss, the higher the risk of cardiovascular disease and death.
Regardless of the degree of obesity in diabetic patients, this correlation was consistently found in underweight, normal weight, overweight, and obese patients.
The research team interprets this as showing that the degree of weight change is more significantly involved in the occurrence of cardiovascular disease in diabetic patients than the degree of obesity.
Professor Kim said, “This study is significant in that it revealed that both rapid weight gain and loss in diabetic patients increase the risk of cardiovascular disease.”
He added, “We should not consider weight loss in obese diabetic patients unconditionally positive. There is a need,” he added.
The results of this study were published in ‘Diabetes Care’, an international academic journal in the field of endocrine metabolism.
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