Detection of Circulating Vaccine-Derived Poliovirus Type 2 in Kenyan Refugee Camp Raises Concerns

2023-08-04 21:38:00

On July 11, 2023, WHO received an official report of the detection of circulating vaccine-derived poliovirus type 2 (cVDPV2) in two cases of acute flaccid paralysis (AFP) and two community contacts of children healthy asymptomatic people from Hagadera refugee camp, Kenyathe second largest refugee camp in the world with more than 100,000 refugees.

The first case is a 2-year-old boy, vaccinated with three doses of oral polio vaccine (OPV), with no travel history, who developed paralysis on May 26, and stool specimens were collected on June 1 and June 2. June. The second case is a 2.7-year-old woman with a travel history to Afmadhow, Lower Juba, southern Somalia, vaccinated with three doses of oral polio vaccine (OPV), who developed paralysis on May 27, and stool samples were collected on June 2 and June 3, 2023.

A community contact, a healthy, asymptomatic 2-year-old boy, was identified through a stool sample collected on May 25, 2023. The child did not receive any doses of vaccine. A second community contact, a healthy asymptomatic child, has also been identified in Hagadera refugee camp with the same strain emerging from Somalia and an investigation is ongoing.

Genetic sequencing analyzes showed that all four isolates are genetically linked to cVDPV2 circulating in Banadir, Somalia.

WHO assesses the overall risk at the national level to be high due to the overcrowded living conditions in the refugee camp, the high rate of malnutrition, inadequate water and sanitation facilities, and the frequent population movements with Somalia.

According to WHO and UNICEF estimates of national immunization coverage, the third dose of oral polio vaccine (OPV3) and the first dose of inactivated polio vaccine (IPV) reached 91% in Kenya in 2021. However, the coverage in Hagadera camp is 77% for OPV3 and IPV in May 2023.

Source: World Health Organization

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