One of the main causes of Alzheimer’s disease is the accumulation of beta–amyloid protein in the brain, where it forms plaques. Scientists from Hokkaido University and Toppan have managed to develop a technology capable of spotting this accumulation. Their blood test actually detects certain biomarkers (beta–amyloid binding exosomes), which increase as beta–amyloid proteins build up in the brain. An advance which for the moment has proven itself… on the mouse.
“In addition to the lack of effective treatments for Alzheimer’s disease, there are few methods to diagnose it,” note the authors. “This pathology can only be definitively diagnosed by a direct examination of the brain through an autopsy. Beta-amyloid buildup in the brain can be measured by cerebrospinal fluid tests or positron emission tomography. However, the first test is extremely invasive, and the second is quite expensive. Thus, there is a need for a diagnostic test which is both economical, accurate and widely available. »
In addition, an early diagnosis would make it possible to set up a treatment as soon as possible, whether medicinal or not (cognitive stimulation, psychological care, speech therapy, etc.).
Alzheimer’s disease: why are women twice as affected?
