2023-06-16 17:14:20
National Cancer Center Professor Seung-Kwon Myeong’s team analysis
“Between the vitamin D group and the placebo group
No significant difference in fall prevention
High calcium may reduce muscle function
When I go to the cooking center with a 3-5 day old baby, I always hear from the person in charge of the neonatal room, “Did you bring vitamin D?” Vitamin D is also mentioned as one of the necessities that expectant mothers should prepare in online mom cafes. In fact, vitamin D is known to play a role in protecting bone health, such as facilitating the absorption of calcium and phosphorus in the intestines and reabsorbing calcium in the kidneys.
As people’s interest in vitamin D has increased these days, more and more hospitals are recommending that vitamin D levels in the body be checked. They are also promoting a prescription that vitamin D can be supplemented with a high-dose intramuscular injection.
However, experts have recently pointed out that vitamin D is not very helpful in preventing fractures. It is explained that it is effective to fill the proper level by steadily consuming fish and mushrooms rather than filling up with vitamin D by intramuscular injection or oral pills.
According to the National Cancer Center on the 15th, Myeong Seung-kwon, a professor at the Department of Family Medicine, who serves as the dean of the Graduate School of International Cancer Research, is working on a meta-analysis of 15 clinical trials published in international journals between 1992 and 2021 to confirm the effect of vitamin D on the human body. embarked on Meta-analysis refers to a research method that integrates various results on a specific research topic into one and statistically re-examines them.
According to the results, supplementation of vitamin D in the form of intramuscular injection or oral administration did not have a clear effect on the prevention of fractures or falls compared to the placebo group. Rather, the research team analyzed that vitamin D administration might increase the risk of falls. Professor Myung said, “Injecting high doses of vitamin D can cause muscle weakness due to hypercalcemia.
Hypercalcemia means a blood calcium level of 10.5 mg/dL or more or ionized calcium of 4.2 mg/dL or more. Too much calcium can cause abnormalities in hormone secretion and muscle contraction. In other words, calcium concentrations above the standard level lead to a decrease in muscle function, which can increase the risk of falls.
The problem is that high-dose vitamin D administration is being abused by the general public because hospitals and clinics have set the normal level of vitamin D in the blood too high. The normal concentration of vitamin D set by hospitals and clinics is 20 to 30 ng/ml. According to this, only the top 2.5% of people with a normal number by that standard. Most people are at a level of 12 to 20 ng/ml, which is lower than the reference point. Professor Myung said, “Since the current recommended intake of vitamin D is not related to a medically healthy state, the concept and definition of the recommended amount must be newly created.
It is argued that only exposure to sunlight is sufficient unless a specific disease is suspected due to a serious deficiency of vitamin D. It is also helpful to eat foods that contain vitamin D, such as salmon, saury, mushrooms, eggs, and cheese. Professor Myung said, “For bone health, it is better to expose yourself to the sun for at least 10 minutes a day to induce vitamin D synthesis naturally. is enough,” he advised.
The results of this study were published last April in ‘Osteoporosis International’, an international academic journal at the Science and Technology Citation Index (SCIE) level in the field of osteoporosis.
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