Dr. Anan Chongkaewwatana, virologist Director of Animal Health and Management Innovation Research Group National Center for Genetic Engineering and Biotechnology (Biotech), National Science and Technology Development Agency (NSTDA) posted on Facebook. Anan Jongkaewwattana specify the message
Read on for a short study just published yesterday on hope. “Covid Vaccine” to be designed to be specific to the Omicron virus. because the vaccine designed for use now uses the spike data of the initial virus strain; and “Covid Vaccine” It seems to work very well. The immune response to the vaccine, especially the antibodies that the vaccine provokes. It has high specificity and has good antiviral effect. This is evidenced by the high efficacy of the vaccine at more than 90%, which exceeded the expectation of 50% when the omikron virus emerged and escaped much of the older vaccines. Attempts to adapt the vaccine to be designed specifically for Omikron have begun. Experience with first-generation vaccines has led to expectations that The second-generation vaccine is likely to be able to induce very high levels of omikron immunity as well. Because they come from spike protein as well. The mechanism of stimulating the immune system should not be very different. But when I saw the topic of this research It doesn’t seem like good news.
The information reported to say Omikron’s spike protein does not have the same immune-boosting properties as the original virus. Although the antibody content of spike protein binding in laboratory animals injected with both the old and the new vaccines was high, the immunostimulating ability of “Covid Vaccine” The design of Spike Omikron is not as good as the original. Important information is Injected rat antibodies “Covid Vaccine” Originally able to inhibit other virus strains such as Alpha, Beta and Delta well and much higher than the landscape from Spike Omikron. disappointing is The immunity to omikron virus from Spike Omikron itself is no different from that of the original Spike.
The researchers also showed other immune system effects besides the inhibitory properties of the antibody, such as T cell content or vaccine-derived T cell activation properties. The use of omikron spikes may not be as straightforward as a vaccine against omikron. “Covid Vaccine” The first generation can be obtained. Various techniques may be needed to add to the new vaccine really…it’s a real challenge for vaccine research circles.