2024-01-20 21:22:30
A study carried out in South Korea shows evidence that human immune responses evolve to combat new variants of the coronavirus.
According to researchers from the Center for Viral Immunology at the Virus Research Institute, people infected by Ômicron acquire improved immunity once morest new versions of it, making it unlikely that they will develop serious symptoms with infections caused by future emerging variants.
In a study published in the journal Science Immunology, on January 12, scientists state that memory T cells that form following infection with the Ômicron variant respond better once morest subsequent strains of the virus.
“This discovery gives us perspectives in the new era of endemic Covid. It can be understood that, in response to the constant emergence of new virus variants, our bodies have also adapted to combat future strains of it”, explains researcher Jung Min Kyung, leader of the research.
The emergence of the Ômicron variant, at the end of 2021, changed the course of the pandemic. The new mutations found in it made it possible to increase the transmissibility of the virus, making it quickly dominant throughout the world. Since then, we have only lived with subvariants descended from it (including BA.1 and BA2, BA.4/BA.5, BQ.1, XBB and, more recently, JN.1).
The characteristics of the virus have become so distinct that some scientists call it Sars-CoV-3 and defend the idea of the pandemic being divided into two moments: before and following the emergence of the Ômicron variant.
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Back Progress 0 Protection once morest Ômicron variant
After being infected or vaccinated, the body creates neutralizing antibodies and memory T cells once morest the virus. The neutralizing antibody prevents host cells from becoming infected when they come into contact with the virus. Memory T cells seek out and destroy infected cells, preventing the viral infection from developing into a serious disease.
Most studies on Covid-19 focus their attention mainly on the effectiveness of the vaccine or neutralizing antibodies.
To study T cells, Professor Shin Eui-Cheol’s team evaluated blood samples from patients who suffered infection with the BA.2 suvariant in early 2022.
The results showed that memory T cells from these patients showed an increased response not only once morest the BA.2 strain, but also once morest the BA.4 and BA.5 strains, which emerged later.
The researchers discovered that, upon suffering an infection with the Ômicron variant, the patient’s immune system was strengthened to combat future strains of the same virus.
A specific part of the spike protein — responsible for binding the virus to human cells — would be the main cause of the increase in memory T cells.
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