2024-07-12 14:48:08
July 12, 2024
People who have never been infected with the SARS-CoV virus exhibit a hitherto unknown immune response that protects them, according to a study just published in Nature. explain.
they are called Norvid. These people have never been infected with Covid-19, despite waves of epidemics since the emergence of SARS-CoV-2. A study published in the journal natureseems to have unlocked their secret.
Researchers have just discovered that people who consistently manage to avoid illness have a unique immune response that helps them avoid long-term infections. Research indicates “An immune response located in the mucosa of the nose that allows an individual to recognize the virus and prevent it from settling and causing infection,” detailed Imperial College Londonthe agencies co-directing the work, in a press release.
Detailed infection routes
To reach these conclusions, the scientists conducted a human challenge study — in which candidates voluntarily became infected with the virus. Thirty-six healthy adults with no history of Covid-19 infection or vaccination once morest Covid-19 were injected with the virus through the nose.
The team conducted detailed monitoring of blood and mucous membranes in the nose before, during and following infection. The entire process from infection to complete resolution is scrutinized. In total, more than 600,000 cells were sequenced!
The team found in each participant their unique immune response. In individuals who immediately cleared the virus, the researchers did not observe a general immune response as we know it, but an immune response developed “Never seen before”, Please note the press release Imperial College. Cells involved in this hitherto unknown immune response can also be identified.
In addition to this finding, the study established an extremely complete chronology of immune system responses during infection. So scientists discovered a gene linked to protection once morest long-term infection.
The starting point for new treatments?
To Professor Chirstopher Chiu, Department of Infectious Diseases, our hospitalImperial College London, “These findings will not only have important implications for the development of next-generation interventions once morest SARS-CoV-2, but are also expected to generalize to other epidemics and pandemics in the future.”
Dr. Marko Likolic, University College London: “These findings shed new light on critical early events that allow the virus to quickly take hold or be eliminated before symptoms develop. We now have a better understanding of the scope of the immune response, which might inform the development of potential treatments and vaccines Base.
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