Corona infection despite vaccination? This new risk factor favors vaccine breakthroughs

  • vaccine breakthroughsalso Corona infections despite multiple vaccinationsare becoming more frequent
  • known so far risk factors are a weakened immune system and a higher one Alter
  • researchers discovered Another factor influencing vaccine breakthroughs: mental illness

Vaccinated three times – and still got Corona! More and more people are getting infected Covid-19despite having been vaccinated once morest the virus. vaccine breakthroughs are no longer a rarity – and continue to increase, the higher the vaccination rate. In addition, the Corona vaccination for many people, especially older people, it is now several months ago. The protective effect decreases over time.

Corona infection despite vaccination: researchers find new risk factor

But under what conditions do people experience vaccine breakthroughs? A US study has now examined which diseases a Corona infection despite vaccination favor.

A increased risk has been mainly older people and People with a weakened immune system attested. In these groups, the vaccination often does not work as well or the effect wears off more quickly. So you are more likely to get infected with Corona despite vaccination and then develop symptoms.

researcher of the San Francisco Veterans Affairs Health Care System have now discovered that there is another factor that risk of vaccine breakthrough elevated. Accordingly, the probability of a corona infection also increases despite vaccination mental illness an.

Research shows that people with mental illness are more likely to have vaccine breakthroughs

The US researchers published the results of their study in the journal JAMA. As Focus Online reported, they evaluated the data from around 260,000 patients over the period from February 2020 to November 2021. Most of the participants were men over 60 years of agewho had already been vaccinated once morest Corona twice and had not been infected before. About half of the patients suffered from one mental illness. Vaccine breakthrough occurred in regarding one-sixth.

The researchers found that the incidence of breakthrough infections was higher in people with mental illness than in those without. According to Focus Online this was still the case following the scientists had taken into account all potential confounding factors such as other illnesses or habits. overweight, Smokingbut also factors such as the type of vaccine might not explain the increased incidence.

According to the study, people with adjustment disorders and those who consumed substances such as alcohol, drugs or caffeine, although they suffered from health or psychological problems, were particularly affected.

This is how researchers explain the link between mental illness and vaccine breakthrough

In their study, the scientists also differentiated between participants over and under 65 years of age. They discovered that the risk of a vaccine breakthrough in people with mental illnesses was increased in both groups. Both older patients, however, the connection was even stronger pronounced than in the younger ones.

The authors of the study put forward two possible explanations for their findings. “Psychiatric disorders, such as depression, schizophrenia and bipolar disorder, have been associated with an impaired cellular immunity and reduced responses to vaccines associated,” they write. Because of this, it is possible that people with psychiatric disorders respond less well to Corona vaccination speak to. It may be that people with psychiatric disorders lose their immunity more quickly or significantly following vaccination.

But the researchers see a possible cause for the vaccine not only in the reaction to the vaccine Association between mental illness and vaccine breakthroughs. “Recent studies suggest that psychiatric disorders are associated with increased involvement risky behaviors associated with contracting Covid-19 can be”, is a second possible explanation. This might also reduce the risk, despite Corona vaccination to infect with the virusbe elevated.

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