2024-08-18 06:00:16
Research into male pattern baldness, a problem that affects around 50% of men worldwide, could benefit from a significant breakthrough thanks to a recent discovery. A team of scientists from the Universities of Sheffield (UK) and COMSATS (Pakistan) have revealed that a sucre Naturally present in the body, 2-deoxy-D-ribose (2dDR), could stimulate hair regrowth by promoting the formation of new blood vessels.
In a study published in Frontiers in Pharmacologythe researchers explain that 2dDR, known for its role in various biological processes, has shown promising effects on models of mouse suffering from hair loss induced by testosterone. This work is part of a research eight years of research into wound healing mechanisms, during which scientists noticed that hair around treated wounds appeared to grow back faster. To confirm this observation, the team developed a mouse model that reproduced testosterone-related hair loss, the main cause of androgenetic alopecia inhomme. Four groups of mice were treated for 20 days: one group with dihydrotestosterone (DHT), another with minoxidil (and medicine current against baldness), a third with a 2dDR gel, and a last one with a combination of 2dDR gel and minoxidil. The results, analyzed in the 21st jourshowed that 2dDR was as effective as minoxidil in stimulating hair regrowth.
According to Sheila MacNeil, professor of tissue engineering at the University of Sheffield, this discovery could offer a natural alternative to current treatments, by improving the blood supply to hair follicles, and therefore promoting hair growth. Muhammed Yar, associate professor at theUniversité COMSATS also points out that 2dDR, in addition to being stable and inexpensive, can be administered through various media, making it a promising candidate for the treatment of alopecia.
However, the researchers stress that these results are still preliminary. Further studies are needed to understand precisely the mechanism of action of 2dDR and determine its relevance in humans. Still, this discovery could potentially lead to more natural and effective treatments for male pattern baldness, an area where options remain limited.
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