Breaking Down Immune Barriers: The Potential of Xenografts and Pig Organ Transplants

2023-10-22 18:21:38

This type of procedure has a name: xenograft, that is to say a graft between different species. This implies the existence of a myriad of immune barriers to break down. Transplants between humans already require finding two donor-recipient candidates close enough to avoid brutal rejection of the organ, so imagine for the organ of a pig…

Even between humans, the recipient will take immunosuppressants throughout his life, the only solution to delay the immune system but which is not without consequences: in particular the increased sensitivity to viral or bacterial diseases given that the drugs force the body to let down its guard.

In the case of transplants, these pigs have been genetically modified to avoid this hyper acute rejection.

But how can this be made possible then? By modifying the genetic heritage of the pig. Research is now focusing on this particularly interesting animal, given the comparable size of its organs, the mastery of its breeding and its great fertility.

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#Eye #Tomorrow #transplanted #pig #organs

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