Pfizer’s bivalent vaccine once morest Covid-19 began to be applied across the country on Monday (2/27). The updated dose with the original coronavirus strain and the Ômicron sublines BA.1, BA.4 and BA.5 is necessary to maintain protection of the population once morest severe disease and deaths.
As occurred in the previous phases of the vaccination campaign, with monovalent doses, it is expected that immunized people present mild and transient adverse reactions in the hours following the injection.
Data from studies on the new Pfizer vaccine, evaluated by the National Health Surveillance Agency (Anvisa) in November 2022, show that local and systemic adverse reactions are, in most cases, of mild to moderate severity, and of short duration. . They are very similar to those reported by the population following the application of first-generation vaccines.
Reactions may include injection site pain, fatigue, headache, muscle aches, chills, joint pain, diarrhea, low-grade fever, and vomiting within the first two days following injection. All of them are provided in the package insert.
“The safety profile of the bivalent vaccines was similar to that known from the original monovalent Comirnaty”, informs Anvisa in the Pfizer vaccine safety assessment.
More intense symptoms?
Post-vaccine events are not expected to be more severe than those seen with monovalent doses. The infectologist at Exame Medicina Diagnóstica, David Urbaez, clarifies that the new generation of vaccines is just a new version that includes the subvariants of Omicron.
“The monovalent one carries the code of the spike protein of the Wuhan variant and the bivalent one has the code of two strains that emerged with the arrival of Omicron. Their content is, strictly speaking, the same. So absolutely nothing has changed in terms of adverse effects,” explains Urbaez.
What to do in case of reaction?
Reactions tend to pass within two days of injection. When feeling uncomfortable, people should rest, hydrate and avoid work activities. Local pain and fever can be resolved with the use of antipyretics such as dipyrone or paracetamol, according to the guidance of infectologist Werciley Júnior, head of the Infection Control Commission at Hospital Santa Lúcia, in Brasília.
If more intense events occur, such as shortness of breath and chest pain, the recommendation is to seek immediate care at an emergency room for diagnostic tests.
“Usually, symptoms are increasingly mild following new doses. The effects that we expect last a maximum of two days”, clarifies Júnior.
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