Beneath the Endless Night Sky, a Generation’s Tomorrow Unravels

A new study revealed that five consecutive hours at night sleep By not taking Depression The risk may increase.

In the past, poor sleep has been considered a side effect of mental illness, but new research shows that the relationship between sleep and mental illness is more complex.

In this research conducted by the researchers of the British University ‘UCL’, it has been reported that people who have a stronger genetic tendency regarding less sleep, that is, people who sleep less than five hours a night, from four Depression symptoms are more likely to develop during the 12-year period.

But in contrast, those with a higher genetic predisposition to depression were not more likely to have poor sleep.

The researchers also found that the link was not specific to those who were genetically predisposed to sleep less and those who regularly slept for five hours or less, regardless of the genetic link. , they were also more likely to have depression.

Lead author Odesa Hamilton, from the UCL Institute of Epidemiology and Healthcare, said: ‘The relationship between sleep duration and depression is like an egg-or-the-chicken scenario. is, meaning they often go hand in hand but which comes first (sleep or depression problem) remains largely unresolved.’

He added: ‘By looking at genetic susceptibility to the disease, we determined that, contrary to what was previously thought, symptoms of sleep disturbance precede depression.’

The researchers used genetic and health data from 7,146 people enrolled in the study from the English Longitudinal Study of Aging (ELSA), with an average age of 65.

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Analysis of genetic and health data showed that less sleep was associated with the onset of depressive symptoms, such as feeling sad or lonely.

Senior author Dr Olesya Ajinkina, from UCL’s Institute of Epidemiology and Healthcare and King’s College London’s Institute of Psychiatry, Psychology and Neuroscience, said: ‘Depression, along with short and long sleep duration, is a major public health problem. play important roles, which are mostly inherited.’

According to him: ‘Polygenic scores, indices of an individual’s specific genetic predisposition, are initially thought to be key to understanding the nature of sleep duration and depressive symptoms.’

Looking at the non-genetic link between depressive symptoms and sleep duration, the researchers also found that people who slept five hours or less were two and a half times more likely to develop depressive symptoms than those who did not. have symptoms, they are three times less likely to be sleep deprived.

The study, published in the scientific journal Nature Translational Psychology, also revealed a link between prolonged sleep and the development of depressive symptoms.

According to the results, those who slept more than nine hours were one and a half times more likely to develop symptoms of depression than those who slept an average of seven hours.

However, depressive symptoms were not associated with more sleep four to 12 years later, consistent with genetic findings.

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Professor Andrew Steptoe, head of the Department of Behavioral Science and Health at the UCL Institute of Epidemiology and Healthcare, said: ‘Poor sleep and depression increase with age and depression and sleep deprivation are increasing worldwide with an aging population. There is a need to better understand the mechanism of the relationship.’

According to him: ‘This study lays the groundwork for future investigations into the intersection of genetics, sleep and depressive symptoms.’

The subjects in the study averaged seven hours of sleep a night.

More than 10 percent slept less than five hours a night at the beginning of the study period, and that number rose to more than 15 percent by the end of the study.

The proportion of those in the depressive symptoms class increased by nearly three percentage points, from 8.75 percent to 11.47 percent.

The study combined data on sleep and depressive symptoms from two Elsa surveys taken two years apart because sleep duration and depression fluctuate over time.

Both sleep duration and depression are partially inherited from one generation to another.

Early studies suggest that depression is about 35 percent heritable and that genetic variation accounts for up to 40 percent of the variation in sleep duration.

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