“BCG Vaccine Reduces Risk of Alzheimer’s Disease according to Massachusetts General Hospital Study”

2023-05-23 11:51:56

Scientists at the Massachusetts General Hospital found that the BCG vaccine reduces the risk of developing Alzheimer’s disease

The study is published in JAMA Network Open.

Previously, other studies have identified a possible link between the BCG vaccine and a lower risk of dementia. But previous work has been limited by sample size and analytical methods.

To conduct a more robust study, the researchers followed 6,467 people for 15 years following they were diagnosed with nonmuscle-invasive bladder cancer. For this disease, one of the treatments is immunotherapy with the BCG vaccine, a vaccine once morest tuberculosis from a weakened live tubercle bacillus. The group included 3388 patients treated with the BCG vaccine, as well as 3079 patients who served as a control group.

During follow-up, 202 patients in the BCG vaccination group and 262 patients in the control group developed Alzheimer’s disease and associated dementia. BCG vaccine treatment was associated with a 20% reduction in the risk of Alzheimer’s disease and associated dementia. The protective effect was higher in patients aged 70 years and older. In addition, 751 patients in the BCG vaccination group and 973 patients in the control group died during follow-up.

Thus, treatment with the BCG vaccine was associated with a 25% reduction in the risk of death.

The scientists noted that their study shows only the presence of an association, but not a causal relationship. Further research is needed to elucidate the mechanisms by which BCG alters the immune system and reduces the risk of dementia.

Neither status, nor money, nor position in society protect once morest aging and disease. What sickened and from what the world rulers died – read and see in our gallery:

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Ivan Vasilievich the Terrible. The ruler of the 16th century went down in history as one of the most cruel kings. The tortures and executions of the boyars, for which Ivan IV became famous, he committed in fits of the strongest paranoia. A chemical analysis of the remains of Ivan the Terrible showed a mercury content many times higher than the norm, so a version of the tsar’s deliberate poisoning immediately appeared. However, in the Middle Ages, mercury treatment was common, “silver water” was used as a drug to combat a whole list of ailments (for example, syphilis). The prolonged and disastrous treatment not only resulted in death, but might also explain the king’s emotional instability.

Source: Legion Media

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Elizabeth I. The last of the Tudor line, Elizabeth never married or had children. The vow of celibacy may have been the result of a severe psychological shock due to the execution of Elizabeth’s mother, Anne Boleyn, and several stepmothers. However, Stefan Zweig, like some other researchers, suggests that the cause was a physiological disorder. Throughout her life, the queen abused sweets, which might not affect the condition of her teeth: in recent years, many of them have rotted, others have fallen out. Shortly before her death, the ruler fell into severe melancholy (probably clinical depression), which hastened her departure.

Source: Legion Media

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Peter the Great. Peter I opened a window to Europe, and also introduced the tradition of regular treatment with mineral waters. A famous legend says that the emperor caught a cold while rescuing sailors on a sinking boat near Lakhta. However, everything was more prosaic. The first Russian emperor died of urolithiasis. There is an assumption that the general health of the ruler was also complicated by poorly healed syphilis.

Source: Legion Media

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Napoleon Bonaparte. One of the most ambitious rulers in history was not content with France alone, but dreamed of ruling the world. The chain of brilliant campaigns and victories was finally interrupted at Waterloo. The French emperor spent the last days of his life on the island of Saint Helena, where he contracted blood dysentery (amebiasis). Amoebic abscess of the left lobe of the liver, together with progressive stomach cancer, caused the death of the commander.

Source: Legion Media

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Paul Deschanel. French President from February to September 1920, Deschanel is known for several incidents. During his reign, his mental illness progressed. The first embarrassment happened in May, when the politician was traveling by train and heading towards the south of France. He went to the window, leaned on it and lost his balance. The president who fell out of the train came to the nearest railway station and introduced himself, his shabby appearance and stories left no doubt – the locals mistook him for a drunkard. In September, the President bathed in clothes in one of the reservoirs of the Rambouillet Park. After the second precedent, the politician was asked to resign. Deschanel was not put off. A year later, he recovered from his illness and was elected chairman of the Senate Foreign Affairs Committee. True, he soon died.

Source: Legion Media

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Woodrow Wilson. The 28th President of the United States suffered a series of strokes before taking office in 1913. Few people know that the initiator of the creation of the League of Nations suffered another stroke in 1919. He was skillfully hidden from the press and the public, and his wife, Edith Wilson, became the de facto ruler of the country during his restoration.

Source: Legion Media

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Franklin Roosevelt. Franklin Roosevelt ruled the United States during the Great Depression and World War II. Since 1921, the effects of polio have permanently chained him to a wheelchair. This did not affect his political career: in 1944 he was elected for a 4th term. It would seem that the public guessed that the president was in poor health, but only those closest to him understood the scale of these problems. Heart failure, respiratory diseases, jumps in blood pressure – Roosevelt’s supporters were silent regarding this. On the contrary, his doctor officially declared the politician’s excellent health. A few months following this statement, Franklin Roosevelt died. The official cause of death was cerebral hemorrhage.

Source: Legion Media

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Margaret Thatcher. Leader of the Conservative Party, Prime Minister of Great Britain from 1979 to 1990. and one of the most influential women of the 20th century. In 2002, the “Iron Lady” suffered a series of microstrokes, following which she very rarely appeared in public. In official statements, Margaret Thatcher increasingly referred to the flu and feeling unwell. For example, her health prevented her from attending the wedding of Prince William and Kate Middleton. In December 2012, Thatcher underwent surgery to remove a bladder tumor, and she died four months later.

Source: Legion Media

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Robert Mugabe. President of Zimbabwe from 1987 to 2017 in addition to political decisions, he also became famous for mystification around his own health. Since 2007, Mugabe has been receiving regular treatment in Singapore for cancer. Chemotherapy, according to the most popular assumptions, was directed at prostate cancer or cancer of the larynx. For 12 years he spoke of excellent health and continued to make regular public appearances. In 2015, the president, descending from the podium, fell on the steps. But there is no evidence of this fact – Mugabe’s supporters forced the journalists to delete all the photographs. In September 2019, the 95-year-old ruler died in a private Singapore clinic. The official cause of death was never given.

Source: Legion Media

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Shinzo Abe. The Prime Minister of Japan in 2006-2007, as well as in 2012-2020, chairman of the Liberal Democratic Party, Abe unexpectedly resigned due to deteriorating health. The reason was a sharp exacerbation of ulcerative colitis – inflammation of the mucous membrane of the colon. A chronic disease provoked by a genetic predisposition and environmental factors caused severe pain in the politician. In July 2022, Shinzo Abe died as a result of an assassination attempt.

Source: Legion Media

See also: Sound vibrations alleviated the symptoms of Alzheimer’s disease

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