After the World Health Organization stated that Covid-19 coronavirus strain “Omicron” or “Omicron” meet “Subspecies BA.2” already in 57 countries, Thailand Department of Medical Sciences Provide information that an infected person was found “Omicron” BA.2 in Thailand is increasing. Preliminary data found can spread more quickly BA.1 by the Department of Medical Sciences there will be surveillance “Subspecies BA.2” by decoding the whole gene to test the severity The ability to dodge immunity from vaccines.
latest Dr. Anan Chongkaewwatana Virologist Biotech NSTDA has posted a message via Facebook. Anan Jongkaewwattana stated that due to mutations on the viral spike protein “Omicron” or “Omicron” Both BA.1 and BA.2 antibodies isolated from previously infected patients tends to be very high to not be able to catch Recently, studies have shown that BA.2 tends to be resistant to almost all developing therapeutic antibodies. The cause is scattered mutations on thorn protein part It is difficult to find antibodies that will escape the mutated portion there. But our bodies can make a wide variety of antibodies, and the results of studies
from natural infections or from vaccinations make us believe There must still be those antibodies that capture the omikron in our bodies, only that it is very difficult and a lot of luck to find and isolate those antibodies from pools that contain many other antibodies.
The good news today is Efforts of researchers competing for antibodies that can catch and stop all types of coviral virus seems to be true by the latest research by a research team from the Netherlands (a long-standing and very strong group of coronavirus researchers) found that one clones of an antibody isolated by the research team was named 87G7 Able to clear the stone stages of both BA.1 and BA.2 Omikron to capture Spike Thorn Protein. and inhibit the entry of virus cells The results of the experimental use of this antibody in laboratory animals exposed to the virus showed that It can prevent infection very well.
The research team conducted an in-depth study. Antibody 87G7 This binds the spike protein at the critical cell entry site (called RBD) at the six amino acid sites (green in the picture) that are currently unchanged in all viral strains. which the omikron group found to change will be the red part. will not match where the 87G7 went into the grip, which may be that This green amino acid location It is difficult to replace because if replaced, the function of the spike protein is ineffective or bad, the virus needs to be stored.
This position is kept unchanged. If so, 87G7 would be an antibody capable of suppressing all virus strains. If the virus does not mutate add to these 6 amino acids.
Dr. Anan concluded that The research we’re currently competing with is amazing, and I believe the 87G7 might not be the only clone we’ll find. There will be more to follow.
