Antibiotic-resistant superbacteria present in hedgehog skin before penicillin

Naturally occurring antibiotic-resistant bacteria… Antibiotics should be used more cautiously

Hedgehogs found to have spontaneously methicillin-resistant Staphylococcus aureus

[Pia B. Hansen 제공/ 재판매 및 DB 금지]

(Seoul = Yonhap News) Reporter Eom Nam-seok = It is known that the so-called super bacteria, which antibiotics do not work, were created when antibiotics were used in hospitals.

However, a new study has found that Staphylococcus aureus (MRSA), which is resistant to the second-generation antibiotic methicillin, arose naturally in hedgehogs regarding 200 years ago, long before the first-generation antibiotic penicillin was used, a new study found.

According to the University of Cambridge, UK, an international research team led by Dr. Ewan Harrison of the ‘Welcome Sanger Institute’ published the results in the scientific journal ‘Nature’ that the bacteria that inhabit the hedgehog’s skin along with fungi that secrete antibiotics developed resistance to MRSA. announced on

As a result of research on hedgehogs living in Denmark and Sweden, the research team found that 60% had ‘mecC-MRSA’, a type of MRSA. mecC-MRSA was first discovered in dairy cows in 2011, and it was assumed that it was caused by an overdose of antibiotics to dairy cows at ranch.

However, the research team found that the hedgehog’s mecC-MRSA first appeared in the early 1800s following using gene sequencing technology to trace the gene that made it resistant to antibiotics.

This confirmed that MRSA did not arise from the use of penicillin, discovered in 1928, but was produced through a natural process.

The research team analyzed that Staphylococcus aureus developed antibiotic resistance in the course of evolutionary competition by living together with ‘Trichophyton erinacei’, a fungus that secretes antibiotics that can kill itself.

The research team pointed out that because almost all of the antibiotics currently used are obtained from nature, those with resistance to them may already exist in nature.

Trichophyton erinasei (center) and methicillin-resistant Staphylococcus aureus (MRSA, left)
Trichophyton erinasei (center) and methicillin-resistant Staphylococcus aureus (MRSA, left)

(Seoul = Yonhap News) The fungus Trichophyton erinasei (center) secretes the antibiotic methicillin, so that all non-resistant Staphylococcus aureus on one side die, while resistant Staphylococcus aureus survives. [Claire L. Raisen 제공/ 재판매 및 DB 금지] [email protected]

“The results of this study show that there is a very large ‘hospital’ in nature where antibiotic-resistant bacteria can live and can easily pass through livestock and infect humans,” said lead author of the thesis, Mark Holmes, professor of veterinary medicine at the University of Cambridge. “It’s a cold warning to be careful when using it,” he said.

MRSA was first detected in patients in 1960, and it is analyzed that one in 200 MRSA infected people will be infected with mecC-MRSA.

However, although hedgehogs have had mecC-MRSA for more than 200 years, it is extremely rare to infect humans, the researchers said.

“Hedgehogs aren’t the only ones with antibiotic-resistant bacteria,” Holmes said. impossible,” he said.

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