2023-10-26 13:12:14
Researchers have identified a potential link between the gut microbiota and Alzheimer’s disease. If these results are confirmed, they might revolutionize current treatment methods.
Researchers from King’s College London and University College Cork have explored an unexpected avenue: the role of the intestinal microbiota in the development of Alzheimer’s disease. Published in the journal Brainthis research was notably presented by Science and Life.
Previous studies have shown that changes in the gut microbiota are a potential risk factor for Alzheimer’s disease, which affects millions of people around the world.
Results that might revolutionize current treatment methods
However, the causal link had not been clearly established. The research team attempted a special graft to clarify this possible link, reports Science and Life. Gut microbiota samples from 69 individuals suffering from Alzheimer’s and 64 healthy people were collected. The microbiota from those suffering from Alzheimer’s was then introduced into 16 young, healthy rats. Another group of 16 rats received the microbiota from healthy participants. Ten days following these transplants, the rats underwent behavioral tests measuring in particular memory.
This research was published in the journal Brain. Among various findings, rats that received the microbiota from sick patients began to present cognitive disorders reminiscent of Alzheimer’s. The other group of rats did not show noticeable changes in their behavior or cognitive abilities.
Targeting the microbiota to slow disease
The researchers conclude in a press release: “This study confirms that the composition of our intestinal microbiota has a causal role in the development of the disease.”
If these results are confirmed, they might revolutionize current treatment methods, by specifically targeting the microbiota to slow down, prevent or even treat Alzheimer’s disease.
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