In approximately 20% of cases, it happens that breast cancer occurs, not in a woman over 50 concerned by organized screening, but in a young woman, in particular because of risk factors (predisposition gene ). The question of treatment then arises if there is a desire for pregnancy: What are the risks of interrupting treatment to get pregnant?
A reassuring new study, called POSITIVE or “Big Time for Baby”, has just been presented at the annual San Antonio Breast Cancer International Congress (Source 1). This indicates that young women with hormone-dependent breast cancer who have interrupted their hormone therapy for the purpose of pregnancy did not experience greater short-term recidivism rates. The occasional interruption of cancer treatment to carry out her pregnancy project would therefore be without danger.
The study was conducted among 518 women aged 42 or less, and presenting a desire for pregnancy. They were followed between December 2014 and December 2019, and agreed to suspend their hormone therapy for regarding two years to try to get pregnant. Before interrupting their treatment, they also followed so-called “adjuvant” hormone therapy for 18 to 30 months, ie introduced following surgical treatment of the tumor or following chemotherapy and/or radiotherapy. These 518 came from 116 hospitals located in 20 countries on four continents.
At this stage of the study,…