2023-05-12 08:00:00
Atherosclerosis involves the deposit of a plaque, essentially composed of lipids (we speak of atheroma) on the wall of the arteries. “Ultimately, these plaques can cause damage to the arterial wall (sclerosis), lead to the obstruction of the vessel, or even rupture, with often dramatic consequences”, indicates Inserm.
Atherosclerosis may be conducive to myocardial infarction.
It is already established that obesity and diet high in cholesterol and fat constitute two risk factors. In fact, obese people are twice as likely to develop heart disease.
A news study published in the Journal of Lipid Research demonstrated that our western eating habits might easily lead to atherosclerosis. The researchers estimate the emulsifiers natural substances present in many high-fat foods alter the functioning of the intestines.
“The normal defenses of intestinal mucosal cells to keep bacteria in the lumen of the intestine are reduced when they absorb large amounts of cholesterol and fat,” the researchers said.
This phenomenon favors inflammation in the body. Cholesterol and fats increase the inflammation thermostat and this accelerates atherosclerosis.
A diet high in fat increases the level of endotoxins in the blood
“Obese people and people with diets high in fat and cholesterol have higher levels of endotoxins in their blood,” said Alan Fogelman, a UCLA professor of medicine and study author. is not at the level of causing sepsis, but it does cause a low level of inflammation.”
The team therefore looked for ways toprevent the entry of endotoxins in the bloodstream. One method they have explored is to use high density lipoproteincalled “good cholesterol”.
“We have created transgenic tomatoes in our laboratory that imitate good cholesterol, a high-density lipoprotein, said UCLA project scientist Arnab Chattopadhyay. These tomatoes, when added to a diet high in fat and cholesterol, help to reduce cholesterol and triglyceridesas well as reducing inflammatory derivatives of phospholipids”.
According to the researchers, it seems that this method of lowering cholesterol and triglyceride levels might be beneficial for obese people at risk of inflammatory diseases such as atherosclerosis, arthritis, lupus, multiple sclerosis and more.
Discover in pictures the foods rich in bad fats and cholesterol to limit as much as possible to prevent atherosclerosis.
1684047411
#highfat #diet #promotes #atherosclerosis
