In England Insulin It has been 100 years since the treatment of the first person in the country Diabetes The method of treatment was changed.
This milestone in the history of medicine was accomplished in 1923 at the Medical School of the University of Sheffield by a patient named Sir Stuart Goodwin, who was associated with the Sheffield steel industry and a philanthropist.
At the time, a diagnosis of diabetes was essentially a ‘death sentence’, with a life expectancy of one to two years at most.
The only treatment during diabetes was starvation, such as the Allen diet which restricted the patient’s intake to at least 400 calories in 24 hours.
But Sir Stuart paid to take part in a clinical trial of insulin and after six months he was back at work unrecognizable by his colleagues.
During the treatment, he also gave money for the treatment of many other patients while doing good deeds.
Sheila Francis, a professor at the University of Sheffield’s School of Medicine and Population Health, told the PA news agency: ‘Now we talk about the effects on the eyes and the feet, but none of that has really happened because people are more Did not live long. Indeed, it was a death sentence.’
He added: ‘Essentially, it was a death sentence because it was only controlled by starvation until the use of insulin, so people didn’t live very long.’
According to Professor Sheila: ‘Good faith is a strong thread throughout the story, which took Goodwin into a clinical trial.
‘So, Goodwin saw the goodness and then showed goodwill to the people of Sheffield by funding their treatment.
‘And then they made huge philanthropic donations within the city and within the UK.’
Professor Francis added that Sir Stuart, born in 1886, was likely diagnosed with type one diabetes when he was 30, but lived to be 83 thanks to insulin treatment.
He explained that recent archive records show that the treatment probably started in February.
The insulin used in the 1923 trial was made in Sheffield using cow pancreas tissue.
A year earlier, a young boy was treated in Toronto, Canada, but the discovery was made in 1921.
The first person from Britain was treated in Edinburgh in August 1922.
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According to Diabetes UK (the organisation), more than 1 million people in the UK today rely on insulin.
Hannah Postels, 38, from Sheffield, was diagnosed with type one diabetes at the age of 26.
“I was diagnosed with type one diabetes in December 2011 and since then I have to inject myself with insulin five times a day to survive,” he said.
He added: ‘Diabetes treatment has come a long way since the first clinical trials in Sheffield 100 years ago and even in the 12 years since my diagnosis.
‘Before I had to stick a needle in my finger to check my blood glucose, but now I wear a sensor on my arm that automatically sends the (glucose) reading to my phone.
‘I will soon start using an insulin pump instead of injecting insulin, my pump and sensor will be connected to each other to help keep my blood glucose levels in a healthy range.’
He added: ‘It is remarkable to think that before the discovery of insulin and the first clinical trials, type 1 diabetes was a death sentence for patients, but 100 years later we have reached a point where more and more patients are able to use this technology. are able to access what is essentially an ‘artificial pancreas’.
‘These improvements make a real difference to people’s lives, reducing the burden of living with a condition that can be very difficult and tiring to manage.
‘As a diabetes patient from Sheffield, I am really proud that the city and university played such a vital role in the first British clinical trials of insulin and everyone involved in the research that has followed since. I am grateful.’
However, Professor Francis said more needed to be done to ensure equal access to life-saving treatment worldwide.
He explained: ‘I think we always try to have equal access to these different medicines around the world and the pharmaceutical companies should manage the availability of insulin around the world at a reasonable price, which is all that has been done so far. is one of the most successful medicines.
A spokesman for Diabetes UK said: ‘Before the discovery of insulin type 1 diabetes was a death sentence, people didn’t live more than a year or two.
‘The discovery of insulin was revolutionary and has saved millions of lives worldwide, turning a deadly condition into something manageable.’
‘In the years since this breakthrough, we have learned an incredible amount about the role of the immune system in type 1 diabetes and its potential consequences for people’s health and well-being.
Diabetes UK is committed to funding research that will lead to new treatments and eventually a cure for type 1 diabetes, while insulin is a thing of the past as a therapy for the condition. .’
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#England #years #trial #insulin #diabetes
2024-09-09 03:06:31
Table of Contents
100 Years of Insulin: A Life-Changing Discovery in the Treatment of Diabetes
It has been 100 years since the first person in England, Sir Stuart Goodwin, was treated for diabetes using insulin at the University of Sheffield’s Medical School in 1923. This milestone in medical history marked a significant shift in the treatment of diabetes, transforming a diagnosis from a “death sentence” to a manageable condition.
The Pre-Insulin Era
Before the discovery of insulin, diabetes was a devastating diagnosis. Patients were forced to follow a strict diet, such as the Allen diet, which restricted calorie intake to a mere 400 calories per day. This punitive regimen was hardly effective, and patients often succumbed to the disease within a year or two.
The Breakthrough
The discovery of insulin was made in 1921 by Sir Frederick G Banting, Charles H Best, and JJR Macleod at the University of Toronto [1[1[1[1[1[1[1[1]. The researchers successfully isolated the hormone insulin, paving the way for its use in treating diabetes. A year later, in July 1922, insulin injection treatment began [3[3[3[3[3[3[3[3].
The First British Clinical Trials
In August 1922, the first person from Britain was treated with insulin in Edinburgh. A year later, in 1923, Sir Stuart Goodwin, a philanthropist and steel industry associate, participated in a clinical trial of insulin at the University of Sheffield’s Medical School. Thanks to insulin treatment, Goodwin was able to return to work after six months, and he even funded the treatment of
History of insulin
100 Years of Insulin: A Milestone in the History of Diabetes Treatment in England
This year marks a significant milestone in the history of medicine – 100 years since the first person in England was treated with insulin for diabetes. The introduction of insulin treatment revolutionized the management of diabetes, transforming a diagnosis that was once considered a “death sentence” into a manageable condition.
The Early Days of Diabetes Treatment
Before the discovery of insulin, diabetes was a devastating diagnosis. The only treatment available was starvation, also known as the Allen diet, which restricted calorie intake to a mere 400 calories per day. This approach was not only ineffective but also cruel, as it left patients weak and malnourished. In fact, a diagnosis of diabetes was equivalent to a death sentence, with a life expectancy of only one to two years at most [[3]].
The Breakthrough
In 1923, a significant breakthrough was made at the Medical School of the University of Sheffield, where Sir Stuart Goodwin, a patient with type one diabetes, participated in a clinical trial of insulin. This trial was a game-changer, as it marked the first time insulin was used to treat diabetes in England. Sir Stuart’s involvement in the trial was not only crucial to the success of the treatment but also demonstrated his philanthropic spirit, as he went on to fund the treatment of many other patients [[1]].
The Impact of Insulin
The introduction of insulin treatment has had a profound impact on the lives of people with diabetes. Insulin helps to regulate blood sugar levels, preventing short-term and long-term complications associated with diabetes, such as blindness and nerve damage [[3]]. Today, over 1 million people in the UK rely on insulin to manage their diabetes, and the treatment has come a long way since the first clinical trials in Sheffield 100 years ago [[5]].
The Story of Sir Stuart Goodwin
Sir Stuart Goodwin, born in 1886, was diagnosed with type one diabetes at the age of 30. Despite the bleak prognosis, he went on to live to be 83, thanks to insulin treatment. His story is a testament to the power of insulin and its impact on the lives of people with diabetes. Professor Sheila Francis, a professor at the University of Sheffield’s School of Medicine and Population Health, described Sir Stuart’s story as one of “good faith” and philanthropy, highlighting his role in funding the treatment of other patients and making significant donations to the city and the UK [[1]].
The Future of Diabetes Treatment
As we celebrate 100 years of insulin, we also look to the future of diabetes treatment. Advances in technology and medicine have transformed the way people with diabetes manage their condition. For example, Hannah Postels, a 38-year-old from Sheffield, was diagnosed with type one diabetes at the age of 26. She now wears a sensor on her arm that automatically sends her blood glucose readings to her phone, making it easier to manage her condition [[5]].
Conclusion
The introduction of insulin treatment in England 100 years ago marked a significant milestone in the history of medicine. From a diagnosis that was once considered a “death sentence” to a manageable condition, insulin has transformed the lives of people with diabetes. As we look to the future, we recognize the importance of continued research and innovation in diabetes treatment, ensuring that people with diabetes can live long, healthy, and fulfilling lives.
References
<a href="https://pubmed.ncbi.nlm.nih.gov/
