Recently, researchers succeeded in alter immune cells of patients so that they recognize mutated proteins specific to their tumors. Once this recognition is made, these immune cells are released to go and destroy those responsible for cancer, depending on the identified protein upstream.
The principle of cancer is the proliferation of cells that have undergone genetic mutations and which propagate in a way uncontrolled. To respond to this disordered proliferation, the body responds with its immune system, and more particularly the immune cells that are the lymphocytes T. On the other hand, even if these cells are adorned with specific receptors to target diseased cells, patients often don’t have enough T cells to fight their disease. Each cancer being a ensemble unique of mutations, the editing of CRISPR genes might come to solve this uniqueness and take over T cells to destroy cancer cells. (source 1)
A forced boost of the immune system
This failure of the immune system might be overcome thanks to the CRISPR genes. To do this, action must be taken at the level of T cell receptors (TCR). By isolating the TCRs,…