Diet and Ovarian Cancer Survival in Black Women

Better Pre-Diagnosis Dietary Quality Linked to Improved Survival in Black Women with High-Grade Serous Ovarian Cancer!

Well, it seems like eating your greens might have a pretty serious (pun intended) impact on survival when it comes to high-grade serous ovarian cancer (HGSOC)! In a recent study, which sounds like it was conducted in the exclusive, intellectual comedy club known as the African American Cancer Epidemiology Study, researchers found that better pre-diagnosis dietary quality is associated with improved survival among Black women afflicted by this rather unfunny form of cancer.

The Study: A Dive into Dietary Patterns

Now, let’s break this down. A group of 483 self-identified Black women, aged 20-79 and freshly diagnosed with histologically confirmed epithelial ovarian cancer (EOC)—that’s fancy jargon for they’ve got the real deal—were recruited for the study that spanned from December 2010 to December 2015. Researchers took a good, hard look at what these ladies were munching on in the year leading up to their diagnoses.

Using two notably intimidating acronyms (Healthy Eating Index-2020 and Alternative Healthy Eating Index-2010), dietary habits were meticulously assessed based on responses from the Block 2005 Food Frequency Questionnaire (yes, you heard it—Food Frequency Questionnaire, as if your food choices were up for jury duty).

Findings: The Fats and The Fabulous

Ready for the punchline? Among the range of dietary patterns assessed, there was precious little to cheer about for the overall trial group—it appears that individual dietary components didn’t do much to help the full sample of women with multiple types of EOC. No significant survival associations were found. Sad trombone, right?

However, for the select club of women with HGSOC, who might be thinking, “Is it too late to swap those fries for a salad?” Well, the results are quite encouraging! Women with better adherence to the Healthy Eating Index-2020 guidelines in the later quartiles—who knew eating your veggies could save you from the grave—had significantly lower mortality rates (HR of 0.63!). That’s right; better food choices directly correlate with lower chances of kicking the bucket. Who knew that kale might just be the superhero of greens?

Practical Takeaways: Can You Eat Your Way Out of Cancer?

Now, before you rush out to buy all the quinoa and chia seeds in town, the authors are quite clear: it isn’t about individual food components—it’s about the *combination* of foods and nutrients that take center stage in the great play of cancer survival. So, as Mr. Gervais would say, “Don’t just snack away! You need a balanced diet, genius!”

Interestingly, there was also the glaring issue of dietary recall bias. You see, the median time between diagnosis and completing those pesky food questionnaires was a whopping 5.8 months! Which means, by that time, remembering what you had for breakfast 4 months ago is about as easy as remembering where you left your keys after a night out. Plus, they didn’t gather post-diagnostic dietary info; because, let’s face it, by then, anyone would be justified in saying, “I really need some comfort food right now.”

Wrapping It Up: A Note of Caution

While this research does provide valuable insights into the dietary narrative surrounding HGSOC, we must remember that correlation is not causation. So before anyone starts claiming that adding more kale salads to their diet guarantees a cancer cure, let’s take a deep breath and not get ahead of ourselves.

Research led by Tsion A. Armidie from Emory University shows promise, but as with all studies, we shall wait for further insights to ensure our snacks won’t be contributing to our premature exits from the stage of life.

In summary, ladies and gents, it appears that dietary quality matters—a lot, at least for the ladies grappling with HGSOC. So, keep those fried foods in check, add a few greens, and remember: in the fight against ovarian cancer, a plate full of nutritious options isn’t just a suggestion; it might just be a lifeline. Cheers to health, and maybe a cheeky salad or two!

Source: JAMA Network Open, published online on October 18, 2023.

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