The results of the study showed that people with one of the blood types, type A, are more likely to suffer a stroke before the age of sixty compared to those with other blood types.
There are four main blood types: A, B, AB, and O. Our blood type (also known as blood groups or blood types) depends on certain antigens, which are molecules that stimulate the immune response, found outside red blood cells.
Even within these major blood types, there are subtle differences that arise from genetic mutations.
The study explored the relationship between the gene responsible for subgroup A1 and the likelihood of having an early stroke.
The researchers examined data from 48 genetic studies, including 17,000 stroke patients and about 600,000 non-stroke individuals, all between the ages of 18 and 59 years.
The researchers conducted a genome-wide study and found two loci strongly associated with the risk of early stroke. Interestingly, one of these sites coincided with the site where the blood type genes were located.
When the researchers looked more closely at specific blood type genes, they found that those whose genome encoded the A1 version of group A had a 16% higher chance of having a stroke before the age of 60 than those with other blood types.
Individuals with the O1 version of group O had a 12% lower risk of stroke.
The increased risks, even for type A, were modest and should not cause concern for those with it, the researchers said.
Although it is still a bit mysterious, the increased risk may be related to components involved in the formation of blood clots, including platelets, the cells that line blood vessels, and various circulating proteins.
It is worth noting that strokes in younger people are rarely caused by atherosclerosis, the accumulation of fatty spots in the arteries. Rather, they are often caused by factors associated with the formation of clots.
In addition, the study determined that people with type B blood have an approximately 11% increased likelihood of having a stroke, regardless of their age.
Previous research has shown that the part of the genome associated with blood type, known as the ABO gene, is linked to calcification of coronary arteries, which can restrict blood flow and increase the risk of a heart attack.
Likewise, the gene sequences for blood types A and B have been linked to a slightly higher risk of venous thrombosis, or blood clots in the veins.
Although more studies are needed to shed light on these discoveries, it appears that our blood type may hold more health secrets than we previously suspected, especially regarding the risk of stroke.
Source: Earth.com
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