2024-08-29 06:00:20
There is still much that is unknown about autoimmune diseases. We invite you to explore new treatment options for multiple sclerosis.
Last updated: August 29, 2024
Multiple sclerosis is a serious, chronic, unpredictable and debilitating disease. Furthermore, its progression can vary from relatively mild to severe. Therefore, it is important to study multiple sclerosis and new treatments.
The disease causes changes or lack of regulation of the immune system and affects the central nervous system (CNS). in other words, It triggers cell destruction in the body itself and affects brain connections with other parts of the body.
What is multiple sclerosis?
Etymologically, MS means “multiple sclerosis or scarring”. This means that important parts of the cells become hardened, inflamed, and subsequently destroyed. Different areas of the brain are most affected.
The brain has an area called white matter. The latter consists of neuronal fibers wrapped in myelin sheath. Neurons are brain cells, and the function of myelin is to transmit brain messages.
Therefore, inflammation of the white matter and destruction of myelin can lead to slowing down or Unable to transmit electrochemical messages between the brain, spinal cord, and other parts of the body.
Symptoms of multiple sclerosis mainly appear between the ages of 20 and 40. However, the diagnosis came too late. Because there is no dedicated test to test this. The risk factors are:
Caucasian female in temperate climate
Also read: Tuberous Sclerosis Global Awareness Day
Multiple sclerosis and new treatments
this Multiple Sclerosis Treatment Mainly involves slowing the progression of the disease and controlling its symptoms. The specific goals are as follows:
Slow down brain damage Slow down the rate of disability and reduce the number of housesImprove brain-body connectionPain relief, support and psychological helpImprove quality of life
Before talking about new treatments, it is necessary to understand what are the basic treatments used to ameliorate this debilitating disease that affects a large number of people around the world. It should be noted that they will not make the disease go away.
Symptom treatment
Its purpose is to improve the quality of life. and reducing symptoms of disease and disability. There are different ways to treat the symptoms of multiple sclerosis. The details are as follows:
Passive rehabilitation Performed by a professional physiotherapistactive recovery by the person himselfInjection therapy Improve the condition of affected musclesdrug treatmentsuch as corticosteroids that reduce inflammationorthopedic surgery Improves alignment of incapacitated tendons, bones and musclesbrain surgery Changes in inflamed or hardened nerve fibers
acute treatment
This symptomatic treatment is more thorough and intense. Used over a shorter period of time when a crisis occurs and people are greatly affected.
New treatment options
As a preventive measure, disease-modifying therapies are used to prevent the appearance of new lesions or the progression of the disease. This therapy is based on immunosuppressive or immunomodulatory drugs.
It helps control immune responses by preventing inflammation or cell self-destruction. In other words, it blocks errors that cause the defense system to recognize certain body parts as foreign objects.
Therefore, the goal of this therapy is to control inflammation and the onset of flare-ups in the short term. This means slowing the progression of disability caused by long-term illness. The drugs used are as follows:
First option: interferon beta and copaxone second-line treatment: natalizumab and fingolimod
New treatments for multiple sclerosis
Unfortunately, treatments for multiple sclerosis are not always very effective. The main reason for this lack of effectiveness is late diagnosis of the disease.
Therefore, it is important to consult a health care professional if disabling symptoms occur. In order to exclude or not exclude this pathology as quickly as possible. Once diagnosed, these new treatments will halt its progression.
All cited sources are thoroughly reviewed by our team to ensure their quality, reliability, timeliness and validity. The bibliographies included in this article are believed to be academically or scientifically reliable and accurate.
GAEM F. Treatment of multiple sclerosis [Internet]. [cited 2020 May 10]. Available from: https://fundaciongaem.org/tratamiento-la-esclerosis-multiple/Cohen M, Maillart E, Tourbah A, De Sèze J, Vukusic S, Brassat D, et al. Switching from natalizumab to fingolimod in multiple sclerosis: a French prospective study. JAMA Neurol. 2014;71(4):436–41.Kappos L, Radue EW, Comi G, Montalban X, Butzkueven H, Wiendl H, et al. Switching from natalizumab to fingolimod: a randomized, placebo-controlled study in RRMS. Neurology. 2015 Jul 7;85(1):29–39. Intramuscular interferon beta-1a therapy is initiated during the first demyelinating event in multiple sclerosis. N England Medical Journal. 2000 Sep 28;343(13):898–904. Stratification and surveillance of risk for natalizumab-associated progressive multifocal leukoencephalopathy: recommendations from an expert panel. J Neurol Neurosurg Psychiatry. 2016 Feb 1;87(2):117–25. Already? roll. 4. Multiple sclerosis and related diseases. Elsevier Limited; 2015. 329–33. García Merino A, Ramón Ara Callizo J, Fernández Fernández O, Landete Pascual L, Moral Torres E, Rodríguez-Antigüedad Zarrantz A. roll. 32. Neurology. Spanish Neurological Society; 2017. 113-9.
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