research A new cheap and simple blood test can help identify people who are at the highest risk of dying from heart failure, has found.
A three-year study found that among patients who had the highest levels of a particular protein Heart Those with low doses were 50 percent more likely to die from a complication.
Testing for this protein, called neuropeptide Y (NPY), can help predict how the risk of heart failure may increase, experts say.
Researchers hope a blood test might be used to help treat heart failure patients within five years.
Neil Haring, Professor of Cardiovascular Medicine and Consultant Cardiologist at the University of Oxford, said: ‘The findings of this study are an exciting new development, building on more than 10 years of collaborative research on stress hormones.
We hope that our research will ultimately benefit the growing number of patients who suffer from the severe effects of heart failure every day.
‘We will then investigate whether high levels of neuropeptide Y can affect whether patients receive life-saving treatment such as ICDs within five years before starting blood tests. can do.’
Heart failure occurs when the heart cannot pump blood around the body as well as it should.
It leads to frequent hospitalizations and reduced quality of life, and there is currently no cure.
At an estimated time United Kingdom More than a million people in the UK suffer from possible heart failure and around 200,000 new people are diagnosed in the UK every year.
Cardiac nerves release NPY in response to extreme stress.
This can lead to potentially dangerously irregular heartbeats and cause the smallest blood vessels in the heart’s nerves to close, causing the heart to work harder and blood to reach the heart. Causes narrowing of the arteries.
The study used data from more than 800 people at different stages of heart failure and measured people’s levels of the hormone B-type natriuretic peptide (BNP), which is currently used to diagnose heart failure. It is a hormone.
Participants’ blood pressure and echocardiogram, a type of ultrasound heart scan, were also taken and monitored regularly.
The study found that people with high levels of NPY, who made up one-third of the group, had a 50 percent greater risk of dying from heart complications over three years than those with low levels. It was more.
Measuring NPY along with BNP may help diagnose heart failure patients, identifying those who may be at higher risk of dying, the researchers say.
Early identification of those at highest risk can also help doctors decide on the best course of action to treat their patients, which can help identify those who are most likely to But life-saving implants can benefit.
The team hopes to have a blood test for NPY in use in clinics within five years.
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Professor Brian Williams, Chief Scientific and Medical Officer at the British Heart Foundation (BHF), said: ‘This new research shows that a new, cheap and simple blood test might help us to find out more accurately in the future. It can help determine which heart failure patients are at the highest risk of early death.
‘Funding life-saving research like this can only go forward and ensure that people with heart failure receive the best and most appropriate treatment so they can live well.’
Funded by the British Heart Foundation Europeans The research, published in the Journal of Heart Failure, was carried out in collaboration with Professor Pradeep Jhand of the University of Glasgow.
Next, the researchers hope to conduct large-scale experiments using data from patients with high levels of NPY to see if it can accurately identify those who may be at risk. But can benefit from life-saving implants.
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2024-07-21 08:02:55
