The primary assessments of the Russian common vaccine towards all sorts of most cancers have been carried out on mice and confirmed good outcomes.
As soon as the know-how is developed, the corresponding drug might be created individually for sufferers with tumors, reported Alexander Guíntsburg, director of the Gamaleya Nationwide Analysis Middle for Epidemiology and Microbiology in Moscow, on the sidelines of the St. Petersburg Worldwide Financial Discussion board, which is being held right here. days.
Based on the director of the Gamaleya middle, the vaccine was developed during the last seven months, in collaboration with a number of Russian most cancers facilities, and financed by the nationwide authorities.
THE VACCINE WILL NOT BE PREVENTIVE BUT THERAPEUTIC
It’s a therapeutic and never preventive vaccine, which might be administered to most cancers sufferers, based mostly on messenger RNA (mRNA) know-how, utilized in COVID vaccines, manufactured by Pfizer and Moderna, the knowledgeable indicated when interviewed by Gazeta. .ru.
“Preventive vaccines are needed for wholesome folks and, on this case, mRNA applied sciences work worse, since they produce extra negative effects. However, if an individual is already sick and preventing most cancers, the advantages of mRNA know-how outweigh these negative effects,” the scientist clarified.
PERSONALIZED VACCINES, ADAPTED TO THE INDIVIDUAL
“From tumor biopsies, we are going to decide what mutations have occurred there and, based mostly on these mutations, utilizing unique nationwide packages, that are presently being developed, to reconstruct the design of the mRNA that may encode the peptides needed to show the immune system to answer the tumor,” Guíntsburg defined.
For the time being, the process to find out the kind of vaccine will final a few month, a interval that’s too lengthy in accordance with the scientist, and he famous that his crew is working to cut back this era considerably.
The experimental vaccine is already working in mice. “We’re testing the vaccine in mice inoculated with melanoma. On day 15, which is when the immune system begins to work, we noticed a giant distinction within the dimension of the tumor between the vaccinated and unvaccinated animals,” mentioned Guíntsburg.
With info from RT
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2024-06-15 07:43:46