2024-03-31 23:00:37
AIDS, once called the “terminal disease of the century,” can now be controlled through drugs and prolong the survival time of patients, but it is still incurable. Recently, a Dutch research team successfully removed the AIDS virus (HIV) from infected cells, bringing hope for a cure for the disease.
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According to foreign media reports, a research team from the University of Amsterdam in the Netherlands stated at the 34th European Society of Clinical Microbiology and Infectious Diseases (ECCMID) pre-conference held this week that they successfully removed DNA on cells through a “scissors”-like operation. The “bad thing (HIV)” prevents it from ever reoccurring once more.
BREAKING: HIV has been completely eliminated from cells in a laboratory, raising hopes of a future cure
Using the tool essentially like scissors, they removed all traces of the virus from infected cells and allowed unwanted genes to be deleted
— Metro (@MetroUK) March 19, 2024
The team stated that the future goal is to completely remove HIV from patients, but this part still needs further research to ensure the safety and effectiveness of the surgery. The entire project is still in the “proof of concept” stage.
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It is understood that this is not the first time that the medical community has tried this innovative treatment. Excision BioTherapeutics, a biotechnology company headquartered in San Francisco, also successfully used CRISPR technology to remove and destroy the HIV virus in three patients last year without causing major side effects.
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Jonathan Stoye, a virologist at the Francis Crick Institute in the UK, said that although there have been some successful cases of this treatment, considering the possibility of off-target effects (that is, CRISPR does not edit the target gene as planned, but instead (altered other genes) and long-term side effects, removing all HIV from the body remains “very challenging.”
Oral hygiene is very important, but if you do the wrong steps, all your efforts may be wasted in a matter of minutes. A dentist pointed out that many people do one thing wrong following brushing their teeth.
Many people brush their teeth once a day in the morning and evening, and use dental floss, mouthwash, etc. to maintain oral hygiene. However, they still have cavities despite taking good care of their teeth. What is going on? In this regard, dentists warn that the problem may be that gargling or using mouthwash immediately following brushing increases the chance of tooth decay.
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The British National Health Service (NHS) recommends that the public brush their teeth with fluoride toothpaste twice a day for regarding 2 minutes each time. Shyaam Vallabh, a dentist practicing in Nottingham, England, said that the concentrated compounds contained in toothpaste can effectively remove plaque during brushing and prevent gum disease and tooth decay. Fluoride can protect teeth from wear and damage. This is one of the best ways to strengthen the hard “protective shell” of your teeth, enamel, and can effectively prevent tooth decay. So keep the fluoride on your teeth as long as possible.
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If you brush or clean your teeth incorrectly, plaque will coat your teeth and cause cavities. “Rinsing your mouth immediately following brushing your teeth will cause the concentrated fluoride in the toothpaste to be washed away by water before it can take effect,” Wallab said. Dentists also point out that if you rinse your mouth immediately following brushing with fluoride toothpaste, the fluoride in the toothpaste will The chemical cannot stay on the surface of the teeth, and its protective power is greatly reduced.
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The NHS also recommends that people just spit out the foam produced by brushing their teeth with toothpaste and do not need to rinse their mouth with water to avoid reducing the effectiveness of fluoride in preventing tooth decay.
“If you brush your teeth and really want to rinse your mouth with water, I recommend waiting at least 30 minutes before rinsing your mouth or eating or drinking,” says Vallabh. “This allows the teeth to absorb the fluoride in the toothpaste and provides More effective protection.” He emphasized that although washing off toothpaste foam will not directly cause tooth decay, repeated mouthwash may increase the risk of tooth decay in the mouth over time.
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In addition, many people like to use mouthwash to maintain fresh breath, and even use it as a “booster” immediately following brushing their teeth, thinking that it is more effective in protecting their teeth. Vallabh points out that this is also inappropriate and will also reduce the enamel-protecting effect of fluoride: “Mouthwash is often used to fragrant breath, but many products have no other benefits for oral health.” He recommends that mouthwash be used throughout the day. It is best to use it during periods other than brushing, such as following lunch, to avoid washing away the fluoride that has just adhered to the teeth.
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