Chinese Woman Infected with Seasonal Influenza A(H3N2) and Avian Influenza A(H10N5) – Health Authorities Issue Statement

2024-01-31 22:55:00

In China, health authorities announced that a 63-year-old woman from the province ofAnhuiwho died at the end of November, had been infected with the seasonal influenza A(H3N2) virus and the influenza A(H10N5) virus, genetically related to the avian subtypes.

The National Administration for Disease Control and Prevention published detailed information on its website, which was translated and posted online by FluTrackers.

The woman’s symptoms began on November 30, 2023, with a cough, fever and sore throat. Authorities said she had underlying health conditions. A few days later, she was hospitalized due to her worsening condition. On December 7, the patient was transferred to a hospital in the province of Zhejiangwhere she died on December 16.

During routine monitoring of samples taken from fatal cases, scientists at the Zhejiang provincial laboratory isolated the seasonal influenza virus H3N2, as well as the H10N5 subtype. Repeated tests by the Chinese Centers for Disease Control and Prevention confirmed these results.

Investigations into the woman’s close contacts in the two provinces revealed no suspected cases, and tests of the contacts were negative.

Scientists carried out complete sequencing of the A(H10N5) virus and found that it was entirely of avian origin and did not have the ability to easily infect humans. Authorities said the woman’s illness was an example of cross-species transmission from poultry to humans. The report does not specify how the woman might have contracted the A(H10N5) virus.

Authorities said the overall health risk was low and there were no signs of human-to-human transmission.

China has already reported a few cases of H10 flu in humans. In 2013, for example, authorities reported a fatal case involving an H10N8 virus carrying genes from the H9N2 avian flu, which circulates in Chinese poultry and occasionally infects humans. The H10 virus has also been detected in Australian slaughterhouse workers and Egyptian infants. In 2021, China reported a case of H10N3 avian influenza in a man in Jiangsu province, the first known case involving this strain. This man had clearly not been exposed to poultry and the virus had not been detected recently in local poultry.

This woman’s infection with the H10N5 virus appears to be the first known case in humans. According to basic information on influenza A virus subtypes provided by the U.S. Centers for Disease Control and Prevention, most H10 virus infections in humans are due to exposure to infected poultry. .

Source : FluTrackers

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