2024-01-28 17:46:08
13 biomarkers discovered through joint research by an international academic research team
Entered 2024.01.27 15:10 Entered 2024.01.27 15:10 Modified 2024.01.26 17:49 Views 752
The number of diabetes patients is increasing. [사진=게티이미지뱅크]Methods have been discovered that can predict the risk of cardiovascular disease in type 2 diabetes patients much more accurately than before.
Medical Express reported that an international academic research team comprised of experts from 23 countries discovered 13 biomarkers that help measure the likelihood of developing cardiovascular disease. This study was led by Johns Hopkins University in the United States, the Chinese University of Hong Kong, and Lund University in Sweden.
In diabetes, high blood sugar itself causes arteriosclerosis, which causes cardiovascular disease. In addition, diabetic patients are often accompanied by hypertension, dyslipidemia, and obesity, which are known as traditional risk factors for cardiovascular disease.
Therefore, cardiovascular disease is considered the most common cause of death in diabetic patients. Compared to people without diabetes, the risk of developing diabetes is 2-3 times higher in men and 3-5 times higher in women. Therefore, diabetic patients need not only blood sugar control but also evaluation and control of various cardiovascular disease risk factors.
Nevertheless, it has not been easy to predict which diabetic patients have a higher risk of developing cardiovascular disease.
“More than 500 million people worldwide have diabetes,” said study co-author Maria F. Gomez, Ph.D. “He said.
To this end, the research team reviewed and analyzed medical studies published since 1990 to examine differences between people with type 2 diabetes who experienced cardiovascular disease and those who did not.
The research team extracted data on 321 biomarkers through a review and analysis of published medical literature. Of these, 13 were found to be significantly associated with cardiovascular risk among people with type 2 diabetes.
The biomarker that stood out the most was NT-proBNP, which monitors the patient’s heart failure status. A simple blood test can be used to check for heart failure. NT-proBNP is a substance produced in large quantities when myocardial cells increase due to heart failure. The research team found that in several studies, the level of NT-proBNP in the body of diabetic patients showed a high correlation with the risk of cardiovascular disease.
“These 13 biomarkers, especially NT-proBNP, require further testing to evaluate their potential value in more studies,” said study co-author Dr. Ronald Ma. “If its value in predicting cardiovascular risk is confirmed, treatment standards may also change,” he explained.
This study was recently published in Communications Medicine.
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