Río Negro produced 50,000 doses of Misoprostol for the termination of pregnancies in hospitals

2023-11-27 08:00:00

Río Negro, with its state laboratory Profarse, stands out in the country as one of the two provinces, along with Santa Fe, that produces Misoprostolthe effective drug for the termination of pregnancywhich guarantees medical care and the legally recognized right to decide for women through its public health network.

The Rionegrina Pharmaceutical Producer Sociedad del Estado (Profarse) is in the final process for the delivery of the last batch of 4,000 doses of Misoprostol 200 milligrams to the Ministry of Health of the province and in this way it will complete some 50,000 doses produced since 2021 to guarantee the drug used by health personnel for the termination of pregnancy.

For 2 years we have been delivering Misoprostol to the Province of Río Negroit does not leave the province, it is for local consumption because it is a product that is not registered at the national level and It is developed at the request of the Ministry of Health“, he explained to RÍO NEGRO Diary Marne Livignigeneral manager of the provincial laboratory that has its plant in Viedma.

The production of Misoprostol Profarse is 200 milligrams in vaginal tablets that are available in a blister of 6 units.. According to the pharmacological description, it is a “uterotonic and cervical ripening agent, synthetic analogue of prostaglandin E1 (PGE1)”.

The production of Misoprostol is established as a public policy, we had 2 years of work developing the formulation and stability checking before releasing it“, explained Livigni, who highlighted that “the laboratory is at the disposal of the public policies of the province.”

Marne Livigni. manager of Profarse, the provincial pharmaceutical laboratory. Archive

For now, the production of Misoprostol is only limited to the internal demand of the province. It does not have authorization from Anmat to leave the jurisdiction and the laboratory does not plan to reach the private sector with its medications in the short term.

The demand of the Ministry of Health had a first stage of 30,000 tablets and a second of 20,000. Now the order must be expected in 2024, according to official estimates from public hospitals.

According to data published over the weekend by the Observatory of Violence once morest Women of Río Negro, in 2022 they were carried out 884 pregnancy terminations in the provincial public sector (both voluntary and legal), 3.6% more than in 2021, when there were 853.

The report details that of the pharmacological procedures that were carried out in Rio Negro hospitals, 27.6% were vaginal, which is the type of tablet produced by Profarse. Most of the treatments were sublingual, with 45.4% and to a lesser extent, with 8.1% in the jugal or buccal form; and 3.5% oral. There are 2.4% of cases that were classified as “not applicable” to the route of administration because no pharmacological intervention was carried out.

Pharmacological interventions can be repeated, which is why the Observatory report clarifies that 12.6% performed two pharmacological interventions and 0.5% needed 3. Only in 4 cases did a third have to be performed. The average number of tablets administered was 12 per treatment, in 82% of cases (725).


Profarse and a booklet of 20 medications


Profarse has the development of regarding 30 medications and dietary supplements and currently produces 20 for the province of Río Negroin its two 3,000 m2 plants located in Viedma, which have certification from the National Administration of Medicines, Food and Medical Technology (Anmat), with a staff of 38 people working.

The list of medications produced by Profarse is extensive, among which are Metformin (for diabetes), Enalapril (for blood pressure that reached a production of 2 million tablets), Albendazole (antiparasitic) and the so-called “orphan drugs” which are drugs that are neglected by the private sector and there is a specific demand.

Furthermore, as highlighted by manager Marne Livigni, at the end of September The contract with the National Ministry of Health was completed, which allowed for the production of 6.5 million sachets of the Fierritas nutritional supplement, which was distributed throughout the country to combat childhood anemia.


80% of public hospitals perform abortions


Río Negro guarantees the voluntary or legal interruption of pregnancy in 29 of its 36 public hospitals and 66 primary health care centers, according to the province’s Observatory of Violence once morest Women, which was announced on Saturday to coincide with the Day of No Violence once morest Women.

In total there are 126 professionals who carry out the internshipsincorporating assistance in Choele Choel, Lamarque and Luis Beltrán, which in 2021 did not have health personnel to carry out the termination of pregnancies.

There are no professionals – due to conscientious objection – in Los Menucos, Sierra Colorada, El Cuy and Guardia Mitre, but in these towns referrals are made to nearby hospitals to guarantee medical care.

Of the professionals involved, 114 are generalists, 25 gynecologists, 10 obstetricians and 2 social workers.

The practices carried out in 2022 are distributed 24.8% in the Alto Valle Oeste region; 24% Andean; 21.6% Atlantic zone; 15.3% Upper East Valley; 12.2% Middle Valley and 2.1% Southern Region.


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