Half-Dose Booster Shot Study: Implications for Global Vaccination Strategy

2023-11-26 02:55:09
A study showed that the Corona vaccine booster shot is effective even if it is only half the basic dose. The research team said, “It will be helpful in the vaccination strategy of low-income countries.” /Graphics=Chosun Design Lab Lee Yeon-ju

A study showed that even if a reduced booster dose of the coronavirus vaccine is administered, an immune response similar to that of the basic dose occurs in adults.

A team of researchers from Australia’s Murdoch Children’s Research Institute (MCRI) and Mongolia’s National Center for Infectious Diseases found that people who had previously received the AstraZeneca and China’s Sinopharm vaccines were given a booster dose of half the Pfizer COVID-19 vaccine, resulting in a similar immune response to those who received the basic dose. It was said that it showed. However, compared to adults who received Russia’s Sputnik V vaccine, half the dose was not effective enough. The research team said, “Reducing the vaccination dose can increase the acceptability of the coronavirus vaccine booster and lower the cost of vaccination.”

The immune effect of the coronavirus vaccine decreases as time passes following receiving the vaccine. For this reason, it is important to maintain vaccine effectiveness by receiving additional vaccinations on a regular basis. In Korea, vaccines developed for prevalent mutant viruses are administered once a year.

The research team analyzed the immune response according to the corona vaccine booster dose in 601 adults from Mongolia. 300 people were administered the basic dose of the vaccine, and 301 people were administered only half. The results showed that the immune response of those who received only half the dose was not inferior to that of those who received the basic dose.

Additionally, people who received only half the basic dose had less local pain due to vaccination, and adverse reactions such as fever, vomiting, diarrhea, and headache were also less common in those who received only half the dose. The research team said, “The results of this study will be helpful in the coronavirus vaccine booster strategy in low-income countries.”

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