2023-08-10 10:50:02
Antimicrobial resistance was responsible for 569,000 deaths in the Americas region in 2019. Lower respiratory tract infections were the most common cause of death, with Staphylococcus aureus and Escherichia coli being the leading pathogens.
Experts from the Antimicrobial Resistance Collaborators studied mortality associated with the development of resistance to antibacterial drugs. Research results published in The Lancet Regional Health-Americas.
Experts estimate that in 2019, there were 569,000 deaths associated with the development of antibiotic resistance in 35 countries in the Americas, and 141,000 deaths attributable to this condition. The most frequent cause of death associated with the development of resistance to antibacterial drugs was infections of the lower respiratory tract and chest (189 thousand deaths). Sepsis (in 169 thousand cases) and peritoneal / intra-abdominal infections (in 118 thousand cases) led to death somewhat less often.
The researchers identified six leading pathogens: Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Streptococcus pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii. Together, these pathogens have caused 452,000 deaths associated with the development of resistance to antibacterial drugs. The leading pathogen-drug combination in drug-resistant deaths was methicillin-resistant S. aureus in 34 countries and ampicillin-resistant E. coli in 15 countries.
The authors estimated the number of deaths associated with antimicrobial resistance in 23 bacterial species and 88 pathogen-drug combinations in the Americas in 2019.
The authors stressed that antibiotic resistance poses a serious threat to modern healthcare. Countries with limited access to antibiotics and basic health care have the highest rates of death associated with antibiotic resistance. There is a need to increase access to modern antibacterial drugs in order to reduce deaths from infections.
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