2023-07-23 06:06:00
A study has found that exercise supplements to increase muscle strength can help prevent Alzheimer’s./Getty Images Korea
Research results have been announced that commercially available muscle-strengthening supplements are effective in preventing Alzheimer’s. Attention is focusing on whether it can develop into a new treatment for Alzheimer’s in the future.
In the latest issue of Cell, an international academic journal, a research team at the Medical Center of the Mirror Age said, “‘Beta-hydroxy beta-methylbutyrate (HMB)’, which is used as an exercise supplement for muscle strengthening, has been shown to help prevent the progression of Alzheimer’s.” HMB is not a prescription drug or steroid. It is an exercise supplement that can be purchased at regular sporting goods stores or online. It is mainly used by bodybuilders and others to increase muscle size and strength by enhancing the effectiveness of exercise. HMB is known to have no side effects even when taken for a long time.
Alzheimer’s disease is a disease that induces dementia and memory loss as amyloid beta, a type of toxic protein, accumulates inside the brain. Amyloid beta aggregates with each other to form protein masses called plaques, and symptoms appear when these plaques inhibit neuronal connections.
The research team analyzed the changes by feeding 5 mg and 10 mg of HMB per 1 kg of body weight to mice with Alzheimer’s, respectively. The results showed that HMB protected learning ability and memory while reducing plaque accumulated in the brain and increasing nerve growth factor. It suppresses Alzheimer’s symptoms by increasing beneficial proteins in the brain and restoring neural connections. This is because HMB acts as a neuroprotective supplement and stimulates nuclear hormone receptors in the brain that regulate fatty acid transport.
The research team said, “If the results of the study using rats are applied to humans as they are, 400 to 800 mg of HMB per person per day will have to be consumed.”
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