Understanding High Ferritin Levels: Causes and Associated Conditions

2023-07-21 14:35:13

Ferritin is a protein that plays an important role since it ensures the storage of iron in the body. But when its concentration in the blood is high, it can reveal different pathologies.

metabolic syndrome

Also called “syndrome X”, metabolic syndrome refers to the coexistence of several abnormalities related to excess fat. In cases of abdominal obesity, diabetes and hypertension, ferritin levels may be high (greater than 300-400 ug/L).

A tumor

A high concentration of ferritin can also be associated with certain tumors, such as leukemia, cancer of the lung, colon, kidney, liver, or with Hodgkin’s disease, a cancer of the lymphatic system.

alcoholism

Another possible cause: alcoholism. Indeed, regular consumption of alcoholic beverages in large quantities can cause an increase in ferritin levels in the blood because alcohol stimulates the synthesis of this protein.

Hemochromatosis

When the ferritin level is very high, it can also be a sign of hemochromatosis, a genetic disease due to excessive intestinal absorption of iron that can affect various organs.

an inflammatory disease

Such a result may be associated with an inflammatory disease, such as osteoarthritis and rheumatoid arthritis, conditions that affect the joints, or even lupus, which manifests itself by cutaneous and/or articulatory symptoms.

HEPATIC DISEASES

Liver disease can also cause elevated ferritin levels in the blood. For example, non-alcoholic fatty liver disease, commonly known as “fatty liver”, is a condition in which the liver accumulates excess fat. This condition can cause liver inflammation and elevated ferritin. Similarly, hepatic cirrhosis, a chronic liver disease characterized by scarring of liver tissue, can also lead to increased ferritin.

KIDNEY FAILURE

Chronic kidney failure can be another cause of high ferritin. The kidneys play a vital role in regulating ferritin levels in the body. When the kidneys are not working properly, they may not remove iron from the body properly, leading to a buildup of ferritin in the blood. Therefore, people with chronic kidney disease may have elevated ferritin levels.

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