How to better personalize smoking cessation interventions?

2023-07-20 10:47:59

Only 7.4% of people who have tried to quit smoking remain abstinent for more than a year. To improve the effectiveness of smoking cessation interventions, ComPaRe, the AP-HP Patients’ Community for Research, surveyed 793 patients and 795 physicians to identify the most important markers to consider in personalizing smoking cessation interventions. This study, coordinated by Dr Alexandre Malmartel of Paris Cité University, was published in the journal Journal of Clinical Epidemiology June 11, 2023.

Tobacco causes 75,000 deaths a year[1]. If more than two thirds of smokers are interested in the idea of ​​quitting smoking, only 7.4%[2] of those who attempted smoking cessation remained abstinent for over a year.

To increase the effectiveness of smoking cessation interventions, the research team sought to identify the best way to personalize them and the criteria to be taken into account during this personalization. the researchers first identified 36 markers that might influence the effectiveness of a smoking cessation intervention in the scientific literature. These markers were, for example, the patient’s psychosocial situation, smoking habits, or financial resources.

The researchers then interviewed 793 patients from the ComPaRe cohort and 795 physicians to prioritize the markers to consider when implementing a smoking cessation intervention.

For physicians, the three most important markers to consider in personalizing smoking cessation were:

  • For physicians, the three most important markers to consider in personalizing smoking cessation were: patient motivation (e.g., Prochaska stage[3]their preferences and their fears (for example the fear of gaining weight).
  • For patients, the three most important markers were motivation to quit, smoking habits (at home/work) and level of addiction.

These results will make it possible to build personalized smoking cessation interventions. taking into account the priorities of both patients and their doctors. Indeed, these interventions are often designed by caregivers, without taking into account the patient’s perspective.

Beyond these results, this study proposed a new participatory method for the development of personalized interventions, which can be reproduced in other medical contexts and for other medical conditions.

On the occasion of this publication, ComPaRe thanks all the participants who contributed to these results and renews its call for participation. By registering on ComPaRe (patients will contribute to advancing public medical research on their disease

[1] Public health France:

[2] Babb S, et al. Quitting Smoking Among Adults – United States, 2000-2015. MMWR Morb Mortal Wkly Rep, 2017

[3] stages of change through which people with an addiction problem go: precontemplation, contemplation, determination, action, maintenance, relapse.

[4] Malmartel A, et al. J Clin Epidemiol 2021.

Créée en 2017 par l’AP-HP, ComPaRe, la Communauté de Patients pour la Recherche rassemble aujourd’hui plus de 50 000 patients volontaires partout en France. Ils contribuent à faire avancer la recherche sur leur(s) maladie(s) chronique(s) en répondant régulièrement aux  questionnaires en ligne des chercheurs, sur la plateforme sécurisée 

Press release, AP-HP of July 10, 2023

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