2023-06-17 05:26:00
Japanese doctors are regarding to achieve a revolutionary cure
A group of Japanese doctors have been working for years on a huge medical project to regrow teeth, which may see the light by 2030.
All humans have 32 teeth and molars. Teeth grow twice in a person’s life, first the milk teeth, and secondly the teeth that accompany a person throughout his life, and they grow between the ages of 6 and 12 years.
Expressive
However, 1 percent of the world’s population suffers from a problem of congenital origin, and because of it, those affected by it lack one or more teeth. In the case of teeth, it is called “dental dysplasia.”
This disease sometimes leads to difficulties related to the consumption of food, but also to the soundness of speech sometimes. From this very point, Japanese researchers began the task of searching for a cure for it.
Tooth regrowth
The medical group is led by Professor Katsuo Takashi at Kyoto University, and the first human tests are scheduled for July 2024.
All of the tests the team of scientists has done so far have been done on mice and ferrets, which suffer from dysplasia.
As a result, scientists discovered a gene that encodes a protein that is involved in the process of tooth growth or non-growth. The researchers concluded that proper or improper tooth development is linked to the action of this gene and this protein.
When the growth is done properly, the protein stops its process once all the teeth have been replaced. Now scientists have discovered an antibody that prevents this protein from shutting down, which might allow new teeth to grow.
And the tests that were conducted on mice and mongooses were successful, and the teeth that were missing grew in them. Can this be applied to humans? This is what scientists will try to find out.
But first, scientists must make sure that this type of test does not pose a medical risk to humans and that its side effects are limited or non-existent.
Preliminary human tests are supposed to be conducted by July 2024 and will be conducted exclusively on those suffering from agenesis of the teeth.
Professor Katsuo Takashi hopes that a complete medical treatment for this type of disease will be ready by 2023.
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