Cascade Study Proposing Inclusion of More Women in Lung Cancer Trials

2023-06-12 08:40:00

The French Cascade study proposes to include more women in 123RF© therapeutic trials

Women are increasingly affected by lung cancer. A French study wants to accelerate the movement and propose to include more in its trials.

The study Cascade reveals in its first data that lung cancer is the leading cause of death among women. The cause is smoking for the majority of cases. With equal consumption, women have a cancer rate twice as high as men. However, they are still insufficient in number in studies.

Include more women in trials

In front of this upsurge cases of lung cancer, it is urgent to include more women in French and international trials. Indeed, the latter are under-represented. The French Cascade study coordinated by the AP-HP wants to accelerate the movement. She asks general practitioners to inform their patients concerned by the subject, so that they participate in this initiative.

The objective is to invite women between the ages of 50 and 74 to benefit from a chest scan if they are smokers or ex-smokers. This scanner will allow the detection of several pathologies linked or favored by tobacco: lung cancer but also coronary disease, emphysema or osteoporosis.

Etude Cascade

This study will take place in four French cities: Paris, Rennes, Grenoble and Béthune where several modes of invitation to screening will be tested, including an invitation joined to that of breast cancer screening by mammography.

Are you a smoker or ex-smoker between the ages of 50 and 74? Join the CASCADE Pilot Study (Lung CANcer Screening by Low Dose CT Scan)

Nearly 400 participants already registered. Contact the team on 06 15 06 58 35 ([e-mail]) and talk regarding it around you. pic.twitter.com/i3kPnQkQ1V

— AP-HP (@APHP) August 31, 2022

Lung cancer in women

In France, the incidence of lung cancer is generally stable, even decreasing, in men and mortality is decreasing. But, this is not the case with women. On the contrary: female incidence and mortality rates have risen sharply since the 1990s. Smoking is the main cause.

23% of French women smoked daily in 2021,
i.e. + 2% compared to 2019.

Addiction Prevention Network

To participate in the study: call 06 15 06 58 35 or send an e-mail to [e-mail].

Advantages of the study: smokers entering the study are offered smoking cessation assistance. The study also shows that this aid is accepted by 75% of active smokers.

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